Results 131 to 140 of about 5,653,234 (281)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 *

Allergy. European Journal of Allergy and Clinical Immunology, 2008
J. Bousquet, N. Khaltaev, Á. Cruz, J. Denburg, W. Fokkens, A. Togias, T. Zuberbier, C. Baena-Cagnani, G. Canonica, C. van Weel, I. Agache, N. Aït-Khaled, C. Bachert, M. Blaiss, S. Bonini, L. Boulet, P. Bousquet, P. Camargos, K. Carlsen, Y. Chen, A. Custovic, R. Dahl, P. Demoly, H. Douagui, S. Durham, R. V. van Wijk, O. Kalayci, M. Kaliner, Y-Y. Kim, M. Kowalski, P. Kuna, L. Le, C. Lemière, J. Li, R. Lockey, S. Mavale-Manuel, E. Meltzer, Y. Mohammad, J. Mullol, R. Naclerio, R. O'Hehir, K. Ohta, S. Ouédraogo, S. Palkonen, N. Papadopoulos, G. Passalacqua, R. Pawankar, T. Popov, K. Rabe, J. Rosado-Pinto, G. Scadding, F. Simons, E. Toskala, E. Valovirta, P. V. van Cauwenberge, D-Y Wang, M. Wickman, B. Yawn, A. Yorgancioglu, O. Yusuf, H. Zar, I. Annesi-Maesano, E. Bateman, A. B. Kheder, D. Boakye, J. Bouchard, P. Burney, W. Busse, M. Chan-Yeung, N. Chavannes, A. Chuchalin, W. Dolen, R. Ėmužytė, L. Grouse, M. Humbert, C. Jackson, S. Johnston, P. Keith, J. Kemp, J. Klossek, D. Larenas-Linnemann, B. Lipworth, J. Malo, G. Marshall, C. Naspitz, K. Nékám, B. Niggemann, E. Nizankowska-Mogilnicka, Y. Okamoto, M. Orru, P. Potter, D. Price, S. Stoloff, O. Vandenplas, G. Viegi, D. Williams   +95 more
semanticscholar   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Feedback between US and UK Prices: a Frequency Domain Analysis [PDF]

This paper decomposes the feedback between US and UK price levels by frequency over the period 1791 to 1990. By adapting Geweke's (1982) method of decomposing the feedback between time series to the case of I(1) time series generated by a bivariate error-
Jahyeong Koo, Paul A. Johnson
core  

Effects of Antiepileptic Drugs, Carbamazepine and Phenytoin, on Plasma Concentrations of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in Japanese Patients With Schizophrenia. [PDF]

Neuropsychopharmacol Rep
Ikawa K, Imura T, Nakamura S, Murata K, Morikawa N, Sakata M, Yasuzawa H, Horikawa N.   +7 more
europepmc   +1 more source

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, 2020
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openalex  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Tracing Early Migratory Neurons in the Developing Nose Using Contactin-2 (Cntn2) CreERT2. [PDF]

Genesis
Amato E, Semon AM, Forni PE.
europepmc   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source