Results 31 to 40 of about 5,873,759 (302)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

High-risk newborns and pervasive developmental disorders [PDF]

open access: yes, 2017
Aim of the paper: Analysis of developmental abilities in high-risk infants, with an emphasis on risk, early screening and early diagnosis of disorders of the autistic spectrum (ASD).
Dukovska, Valentina   +3 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Measurement of D0, D+, D*+ and D s + production in Pb-Pb collisions at s N N = 5.02 $$ \sqrt{{\mathrm{s}}_{\mathrm{NN}}}=5.02 $$ TeV

open access: yesJournal of High Energy Physics, 2018
We report measurements of the production of prompt D0, D+, D*+ and D s + mesons in Pb–Pb collisions at the centre-of-mass energy per nucleon-nucleon pair s N N = 5.02 $$ \sqrt{s_{\mathrm{NN}}}=5.02 $$ TeV, in the centrality classes 0–10%, 30–50% and 60 ...
The ALICE collaboration   +1003 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

N-[4-(β-d-Allopyranosyloxy)benzylidene]methylamine

open access: yesActa Crystallographica Section E, 2009
The title compound, C14H19NO6, was synthesized by the condensation reaction between hecilid (4-formylphenl-β-d-allopyranoside) and methylamine in methanol.
Shu-Fan Yin   +4 more
doaj   +1 more source

Forest Gothic of D. N. Mamin-Sibiryak

open access: yesФилологический класс, 2023
The article analyzes a micro detail of D. N. Mamin-Sibiryak’s landscape poetics: the metaphorical epithet Gothic in descriptions of coniferous forests of the Urals, its semantic role, and genesis.
doaj   +1 more source

Tree-level UV completions for N R SMEFT d = 6 and d = 7 operators

open access: yesJournal of High Energy Physics, 2023
We study ultra-violet completions for operators in standard model effective field theory extended with right-handed neutrinos (N R SMEFT). Using a diagrammatic method, we generate systematically lists of possible tree-level completions involving scalars,
Rebeca Beltrán   +2 more
doaj   +1 more source

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