Results 51 to 60 of about 5,653,234 (281)

Безбедна електронÑка пошта [PDF]

open access: yes, 2016
изваР...
информатика, МЕДИС -
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Clostridium difficile Strains Associated with Nosocomial Infections - Laboratory Diagnosis, Prevalence, Susceptibility and Molecular Characterization of the Isolates [PDF]

open access: yes, 2015
Иако во минатото не и Ñе придаваше големо значење на оваа бактерија, Ð´ÐµÐ½ÐµÑ Clostridium difficile е еден од најзначајните агенÑи кои Ñе поврзуваат Ñо Ð¸Ð½Ñ ...
Mihajlov, Kiril, Trajkovska Dokic, Elena
core   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Screening for Diabetes Type 2 in Primary Health Care [PDF]

open access: yes, 2015
Вовед. Инцидената на Ð´Ð¸Ñ˜Ð°Ð±ÐµÑ‚ÐµÑ Ñ‚Ð¸Ð¿ 2 е во пораÑÑ‚. Во делот на раното откривање потребно е да Ñе најде интервенција која најдобро ќе ја препоР...
Iliev, Darko   +2 more
core   +2 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

The Role of Exhaled Nitric Oxide in Childhood Asthma Management [PDF]

open access: yes, 2015
ÐÑтмата претÑтавува хронична инфламаторна болеÑÑ‚ на дишните патишта која Ñе карактеризира Ñо реверзибилна бронхообÑтрукција и појава на Ñимп
Jovkovska-Kaeva, Biserka   +1 more
core   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

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