Results 121 to 130 of about 6,151,612 (256)

ÐолÑÑение ÑÑабилÑной ÑоÑÐ¼Ñ Ð¿Ð»Ð°Ð·Ð¼Ð¸Ð´Ð½Ð¾Ð¹ ÐÐРиз ÑÑамма E. COLI DH10B/R

, 2017
Анатолий Анатольевич Ельцов
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

ÐналÑз ÑÑнкÑÑÑ Ð½Ð¸Ñок Ñ ÑвоÑÐ¸Ñ Ð½Ð° ÑÑеÑеÑолÑÑÑаз, ÑÐºÐ¸Ñ Ð»ÑкÑвали за Ð´Ð¾Ð¿Ð¾Ð¼Ð¾Ð³Ð¾Ñ ÐµÐ½Ð´Ð¾ÑкопÑÑÐ½Ð¸Ñ Ð¼ÐµÑодÑв, залежно вÑд ÑеÑмÑнÑв пеÑебÑÐ²Ð°Ð½Ð½Ñ ÐºÐ¾Ð½ÐºÑеменÑÑв Ñ ÑеÑоводÑ

, 2015
Р. О. Білоруський, Ю. Б. Борис, В. В. Дмитріенко   +2 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Exploring causal correlations between oily fish intake and multiple sclerosis: A two-sample Mendelian randomization study. [PDF]

Asia Pac J Clin Nutr
Chang S, Shi K, Zhang M.
europepmc   +1 more source

РазÑабоÑка бизнеÑ-плана пÑедпÑиÑÑиÑ

, 2017
Анастасия Сергеевна Цыганова
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

D. Seifried, N. Stark: Energiedienstleistungen - Rezension

Technikfolgenabschätzung – Theorie und Praxis, 1994
Torsten Fleischer
doaj   +1 more source

Evaluation of practices for the diagnosis and monitoring of cytomegalovirus infection in kidney transplant recipients in Brazil. [PDF]

J Bras Nefrol
Hatem NA, Keitel E, Santoro-Lopes G, Pierrotti LC, Pasqualotto AC.   +4 more
europepmc   +1 more source

РазÑабоÑка пÑедложений по ÑовеÑÑенÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÑоÑм кÑедиÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑидиÑеÑÐºÐ¸Ñ Ð»Ð¸Ñ (на пÑимеÑе ÐÐР«СбеÑбанк»)

, 2018
Вели Яралиев
openalex   +1 more source