Results 241 to 250 of about 6,151,612 (256)

Vitamin D deficiency in sickle cell disease: a neglected comorbidity in Tunisia. [PDF]

Ann Hematol
Othmani M, Amri Y, Jouini Y, Ouali F, Chelbi S, Hadj Fredj S, Dabboubi R, Messaoud T.   +7 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Correction: Maltman et al. <i>Brevundimonas aurifodinae</i>, sp. nov., an Aerobic Anoxygenic Phototroph Resistant to Metalloid Oxyanions Isolated from Gold Mine Tailings. <i>Microorganisms</i> 2024, <i>12</i>, 2167. [PDF]

Microorganisms
Maltman C, Messner K, Kyndt JA, Yurkov V.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Association of Serum Vitamin D With Macular Microvascular Structure in Type 2 Diabetic Mellitus Without Diabetic Retinopathy: A Cross-Sectional Study. [PDF]

J Diabetes Res
Yang H, Ma X, Pan Y, Zheng S, Zheng H, Xia Z.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Dissemination of study results to participants in mental health research: a meta-research review of studies published in high-impact psychiatry journals. [PDF]

BMJ Open
Pierson G, Nassar EL, Adams C, Boruff J, Nordlund J, Hu S, Rice DB, Thombs-Vite M, Co N, Cook V, Thombs BD.   +10 more
europepmc   +1 more source

Qualitative study of information needs in advanced ovarian cancer: communication among patients, caregivers and healthcare providers regarding the disease, pharmacological treatment and non-pharmacological support. [PDF]

BMJ Open
Rubio Pérez MJ, Sánchez-Heras AB, Maximiano Alonso C, García García Y, Alfaro Oliver N, Marcos Corrales R, Rubio Renau R, Solà Marsiñach C, Bolea Bosque S, Quindós Varela M.   +9 more
europepmc   +1 more source