Results 31 to 40 of about 5,858,804 (256)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Загадочное зырянское слово абутор ’медведь-самец в пору течки’ [A Mysterious Komi Zyrian Word: абутор ’male bear in heat’] [PDF]
Linguistica UralicaThe paper investigates the Russian dialectal word абÑÑÐ¾Ñ âmale bear in heatâ and its later fixation абÑÑоÑÑ âwalking (not hibernating) bearâ. The author proposes to discuss its new interpretation.
Galina Fedyuneva
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
ZooKeys, 2013 The illustrated descriptions of eight new species of the genus Dinotrema with either the propodeum mainly sculptured ora large propodeal areola from Spain are provided, viz. D. amparoae sp. n., D. benifassaense sp. n., D. lagunasense sp. n., D.
Francisco Javier Peris Felipo +2 more
doaj +1 more source
Improving the Gilbert-Varshamov bound for $q$-ary codes [PDF]
Discrete Mathematics & Theoretical Computer Science, 2005 Given positive integers $q$, $n$ and $d$, denote by $A_q(n,d)$ the maximum size of a $q$-ary code of length $n$ and minimum distance $d$. The famous Gilbert-Varshamov bound asserts that $A_q(n,d+1) \geq q^n / V_q(n,d)$, where $V_q(n,d)=\sum_{i=0}^d ...
Van H. Vu, Lei Wu
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Riscos associados à água destinada ao consumo humano e as vulnerabilidades das populações urbanas
Revista Eletrônica de Gestão e Tecnologias Ambientais, 2015 O s e r h u m a n o s e e n c o n t r a e x p o s t o a d i v e r s o s t i p o s d e r i s c os c o m r e c o n h e c i d o s e f e i t o s à s a ú d e .
Luis Henrique Batista Gois
doaj +1 more source