Results 231 to 240 of about 8,577,543 (295)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Effect of ultrasonic-assisted hot-air drying on the quality and drying kinetics of Taraxacum mongolicum. [PDF]

Ultrason Sonochem
Wei MH, Yang L, Fan XQ, Zhou XM, Yang Y, Zhou YC, Chen JJ, Pu CJ, Shi WZ, Xiao SW, Chen PD, Zhou GS, Li C, Yan H.   +13 more
europepmc   +1 more source

СÐÐТÐÐÐ, ТÐÐÐÐÐ ÐÐ¥ РÐЦÐÐЦÐЯ РФÐÐÐСÐФÐÐ Ð.ÐÐÐÐÐЯ

, 2016
Я. Ю.; Київський Національний Університет імені Тараса Шевченка Угляр
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

D-amino acid aminotransferase1 regulates grain chalkiness in rice by modulating endoplasmic reticulum stress response. [PDF]

Proc Natl Acad Sci U S A
Dong H, Lei J, Tian Y, Liu J, Yang H, Jiang X, Zhang R, Zhang Y, Chen R, Bao Y, Liu F, Ren Y, Lu Y, Liu X, Liu S, Yang X, Duan E, Teng X, Wang Y, Gu C, Zhang Y, Chen X, Zhang Y, Xu H, Sha R, Xu X, Li R, Li G, Wang Y, Wan J.   +29 more
europepmc   +1 more source

Ï×üàææ¶æ ÿô˜æ ∙ð ßÙ ×𢠶»Ùð ßæ¶è ¥æ» ∙æ ÕýæØôÈæ§Åæ ÂÚ ÂǸÙð ßæ¶æ ÂýÖæß

, 2013
â ́ÁØ ∙ä×æÚ àæ×æü
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

»ñÚU âÚU·¤æÚUè â´»ÆÙô´ ·¤è ÕæÜ çàæÿææ ×ð´ Öêç×·¤æÑ ÙñÙèÌæÜ ÁÙÂÎ ·ô¤ â´ÎÖü ×ð´

, 2018
çÂýØ ́·¤æ ÙèÚUÁ M¤ßæÜè, ÂêÙ× ·¤é×æÚUè   +1 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Modulation of the nutritional, metabolomic and microRNA profile of colostrum and piglet performance via a high-energy, high-lysine transition diet in sows. [PDF]

J Anim Sci Biotechnol
Luise D, Bencivenni S, Zurru A, Serra A, Laghi L, Correa F, Palumbo F, Trevisi P.   +7 more
europepmc   +1 more source