Results 191 to 200 of about 6,270,790 (278)
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Do adults with cardiovascular disease risk show meaningful reactivity to physical activity measurement? Coordinated analysis across six studies. [PDF]
Arigo D +8 more
europepmc +1 more source
Ðneta; УнÑвеÑÑиÑÐµÑ ÐаÑÑÑ ÐÑÑÑ-СклодовÑÑÐºÐ¾Ñ Michalska-Warias
openalex +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions. [PDF]
Aksel AB +9 more
europepmc +1 more source
ÐÑлом ÐÑмоновиÑ; ÐаÑионалÑнÑй ÑнивеÑÑиÑÐµÑ Ð£Ð·Ð±ÐµÐºÐ¸ÑÑана им. ÐиÑзо УлÑгбека ТÑйÑиев
openalex +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

