Results 81 to 90 of about 6,426,247 (249)

Загадочное зырянское слово абутор ’медведь-самец в пору течки’ [A Mysterious Komi Zyrian Word: абутор ’male bear in heat’] [PDF]

open access: yesLinguistica Uralica
The paper investigates the Russian dialectal word абутор ’male bear in heat’ and its later fixation абуторь ’walking (not hibernating) bear’. The author proposes to discuss its new interpretation.
Galina Fedyuneva
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

ТранÑпериотонеална радикална нефректомија во третманот на карциномот на бубрег: компликации

open access: yes, 2016
Ðаnравен е преглед на наашето хируршко иÑкуÑтво Ñо интра и поÑтоnеративните компликации, документирано кај 275 паци­ÐµÐ½Ñ‚и Ñо карциноми на бубрег
ПетровÑки, Д   +1 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Причини и поÑледици на повредите на градниот кош во мирновременÑки и воени уÑлови

open access: yes, 2017
We had 107 patients with chest injuries – 95 of them were blunt wounds and 12 were wounds from weapons (rifles, revolvers, shotguns, knives, bayonets ...).Chest injuries are, as serious in the peaceful-time, as in the military conditions. They bring into
Јевтиќ (Jevtikj), Миодраг (Miodrag)   +2 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Ticraḍ, gar usemres d wazal n yizamulen i d-mmalent

open access: yesUssnan
This contribution aims to describe the practice of tattooing in some Amazigh regions. It tries to list the different techniques, the actors plus the means used to succeed in this practice which has a high value in the society.
Ourida AISSOU
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Инциденција и преваленција на тироиден карцином во Република Маке- донија (1999-2010)

open access: yes, 2017
Epidemiological data indicates that  thyroid carcinoma (TC)  is the most frequent endocrinological tumors, participating with around 1%  from all malignomas.
Маказлиева (Makazlieva), Тања (Tanja)   +3 more
core  

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