Results 21 to 30 of about 448 (190)

The system of additional capitalization of banks has not yet begun to work in full force [PDF]

, 2015
Original title in Russian is СиÑтема докапитализации банков пока не начала работать в полную ÑиР...
Vilenovich, Perchyan Andrey
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Since the beginning of the capitalization program, banks have paid fines in the amount of 812.7 million rubles [PDF]

, 2018
Original title in Russian is С начала проÐóраммы докапитализации банками уплачено штрафов на Ñумму 812,7 млн рубР...
Russian Federation: Accounts Chamber of the Russian Federation
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

From the beginning of additional capitalization to July 1, 2017, additional capitalized banks provided the economy with about 13.7 trillion rubles in credits [PDF]

, 2017
Original title in Russian is С начала докапитализации по 1 Ð¸ÑŽÐ»Ñ 2017 Ðó. докапитализированные банки предоÑтавили в Ñкономику порÑдка 13,7 трлн руб.
Russian Federation: Accounts Chamber of the Russian Federation
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

On Amending Article 11 of the Federal Law On Insurance of Individual Deposits in Banks of the Russian Federation and Article 46 of the Federal Law On the Central Bank of the Russian Federation (Bank of Russia) [PDF]

, 2014
Original title is О внеÑении изменений в Ñтатью 11 ФедеральноÐóо закона О Ñтраховании вкладов физичеÑких лиц в банках РоÑÑийÑкой Федерации и Ñтатью 46 Ф
Russian Federation: Federation Council
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

ЕФЕКТИ ÐÐ CYP3A4 ГЕÐЕТСКИ ПОЛИМОРФИЗÐÐœ ВРЗ ПОСТОПЕРÐТИВÐÐТРПОТРОШУВÐЧКРÐРФЕÐТÐÐИЛ ПРИ ТРЕТМÐÐ ÐРПОСТОПЕРÐТИВÐÐТРБОЛКР[PDF]

, 2017
Минималната ефективна концентрација на опиоиден аналгетик може значајно да Ñе разликува меѓу пациентите.
СпировÑка, Татјана, Сељмани, Реџеп, ТрајковÑки, Ѓорѓи, ÐамбазовÑка-ТрајковÑка, Вања, Ðојков, Јордан, МатевÑка-ГешковÑка, Ðадица, Карталов, Ðндријан, КузмановÑка, Биљана, ДимовÑки, ÐлекÑандар   +8 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source