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Results 91 to 100 of about 4,891 (158)

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo +3 more
wiley +1 more source

Ð˜Ð¡Ð¥Ð ÐÐÐÐ¢Ð Ð˜ ÐˆÐÐ’ÐÐžÐ¢Ðž Ð—Ð”Ð ÐÐ’ÐˆÐ• – Ð¡ÐžÐ¡Ð¢ÐžÐˆÐ‘Ð, ÐŸÐžÐ›Ð˜Ð¢Ð˜ÐšÐ˜ Ð˜ ÐŸÐ Ð•Ð”Ð˜Ð—Ð’Ð˜Ð¦Ð˜

Sparse Pd–Te Covalent Bridges Drive Anomalous Bulk‐to‐Monolayer Electronic and Magnetic Evolution in FePd2Te2

Advanced Science, EarlyView.
Bulk FePd2Te2 contains sparse interlayer Pd–Te covalent bonds, giving it unexpectedly low exfoliation energy and enabling van der Waals‐like exfoliation. Cleaving these bonds during exfoliation makes the monolayer magnetically distinct from the bulk: magnetic anisotropy energy increases, and the strain‐response coefficient of the magnetic moment ...
Huaiyuan Zhao +7 more
wiley +1 more source

, 2016
Kinetics of tritium labeled coÐ³tisol was performed in control rats, rats treated with Synacthen Depot and rats treated with Dexamethason i.m. Rats were injected with 2 microCuri directly into the lateral tail vein and timed samples were collected by ...
ÐˆÐ°Ð½ÐºÑƒÐ»Ð¾Ð²ÑÐºÐ¸ (Jankulovski), ÐÐ¸ÐºÐ¾Ð»Ð° (Nikola) +2 more
core

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai +12 more
wiley +1 more source

Evidence from CD spectra and melting temperatures for stable Hoogsteen-paired oligomer duplexes derived from DNA and hybrid triplexes. [PDF]

Nucleic Acids Res, 1999
Hashem GM, Wen JD, Do Q, Gray DM.
europepmc +1 more source

, 2017
Basal levels of ACT and cortisol in the plasma show diurnal, menstrual and gravidities variations. Several authors have presented mean value with large deviations making difficulties in the clinical interpretation of the results.In order to get more real
ÐÐ¸ÐºÐ¾Ð´Ð¸Ñ˜ÐµÐ²Ð¸Ñœ (Nikodijevikj), ÐžÐ»Ð³Ð° (Olga) +1 more
core

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source

Classical Path Methods in Line Broadening. I. The Classical Path Approximation. [PDF]

J Res Natl Bur Stand A Phys Chem, 1969
Smith EW, Vidal CR, Cooper J.
europepmc +1 more source

, 2016
Was to present disease, over a patient review of policystic kidney disease, that need hospitalization many times – because of complications that follow it (uroinfection, calculosis, anaemia, chronical kidney insufficiency, hypertension, and cistes crack ...
ÐœÐ¸Ð»ÐµÐ½ÐºÐ¾Ð²Ð¸Ñœ (Milenkovikj), Ð—Ð²Ð¾Ð½ÐºÐ¾ (Zvonko) +1 more
core