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dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of <i>Leishmania major</i> Growth. [PDF]

open access: yesDrug Des Devel Ther
El Hassab MA   +12 more
europepmc   +1 more source

Multi-omics profiling of sow colostrum and faecal microbiota reveals parity-dependent and independent factors associated with piglet survival and growth. [PDF]

open access: yesJ Anim Sci Biotechnol
Luise D   +9 more
europepmc   +1 more source

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