Results 61 to 70 of about 5,871,737 (255)
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile+8 more
wiley +1 more source
ÐаметившиеÑÑ Ð² поÑледнее Ð²Ñ€ÐµÐ¼Ñ Ñ‚ÐµÐ½Ð´ÐµÐ½Ñ†Ð¸Ð¸ к универÑализации образованиÑ, прагматичный подход и ориентирование на потребителÑ, определÑÑŽÑ ...
Елена ВаÑилевÑкаÑ
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The genus Diolcogaster Ashmead, 1900 (Hymenoptera, Braconidae, Microgastrinae) from China
The genus Diolcogaster Ashmead, 1900 (Hymenopteran, Braconidae, Microgastrinae) from China is revised and keyed, with nine new species, namely D. bifurcifossa sp. n., D. brevivena sp. n., D. grammata sp. n., D. ineminens sp. n., D. laetimedia sp.
Jie Zeng, Jun-Hua He, Xue-xin Chen
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Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Riscos associados à água destinada ao consumo humano e as vulnerabilidades das populações urbanas
O s e r h u m a n o s e e n c o n t r a e x p o s t o a d i v e r s o s t i p o s d e r i s c os c o m r e c o n h e c i d o s e f e i t o s à s a ú d e .
Luis Henrique Batista Gois
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Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke+2 more
wiley +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
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Ticraḍ, gar usemres d wazal n yizamulen i d-mmalent
This contribution aims to describe the practice of tattooing in some Amazigh regions. It tries to list the different techniques, the actors plus the means used to succeed in this practice which has a high value in the society.
Ourida AISSOU
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A restriction estimate for a class of oscillatory integral operators along paraboloid
In this paper we establish a restriction estimate for a class of oscillatory integral operators along a paraboloid, Pd−1:={(x1,…,xd):xd=x12+⋯+xd−12}.
Shaozhen Xu, Wenjuan Li
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Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source