Results 151 to 160 of about 4,894 (164)

A Power‐Efficient Monte Carlo Framework for Nonlinear Light–Matter Interactions: In Silico Modeling of Spontaneous and Stimulated Raman Scattering in Turbid Media

Journal of Raman Spectroscopy, EarlyView.
Power‐efficient Monte Carlo modeling of nonlinear light–matter interactions in turbid media is demonstrated using Apple Silicon–accelerated photon transport. The Metal‐base framework enables accurate simulation of spontaneous and stimulated Raman scattering, revealing detection‐dependent SRS efficiency while providing a scalable, energy‐efficient ...
Ilya Vladyko, Vladislav Yakovlev, Alexander Doronin   +2 more
wiley   +1 more source

Comparing treatment outcomes of prolonged exposure therapy across trauma type and veteran status

Journal of Traumatic Stress, EarlyView.
Abstract This retrospective cohort study evaluated the effectiveness of prolonged exposure therapy (PE) across trauma types (combat, terror, civilian) and veteran status (military veterans vs. civilians) in a real‐world clinical setting. We hypothesized that individuals who experienced combat‐ and terror‐related trauma would have higher baseline ...
Nitsa Nacasch, Roy Aloni, Chen Avni, Lilach Rachamim, Edna Foa, Paz Toren   +5 more
wiley   +1 more source

Veterans’ positive parenting practices and satisfaction over time: Examining the impact of moral injury, posttraumatic stress, and internalizing symptoms

Journal of Traumatic Stress, EarlyView.
Abstract Little is known about the association between moral injury (MI) and parenting. Although there is evidence that psychological symptoms impact veterans’ parenting, few longitudinal studies exist. The current study used parallel process latent growth curve models to explore the effects of MI and other psychological symptoms on positive parenting ...
Ryan P. Chesnut, Jennifer K. Karre, Cameron B. Richardson, Keith R. Aronson, Daniel F. Perkins   +4 more
wiley   +1 more source

Efficient First‐Principles Inverse Design of Nanolasers

Laser &Photonics Reviews, EarlyView.
This article introduces a first‐principles inverse‐design framework for nanolasers that directly incorporates nonlinear lasing physics. By unifying steady‐state ab‐initio laser theory (SALT) with topology optimization, it reveals how spatial hole burning, gain saturation, and cavity‐emitter coupling shape laser performance, enabling efficient discovery
Beñat Martinez de Aguirre Jokisch, Alexander Cerjan, Rasmus Ellebæk Christiansen, Jesper Mørk, Ole Sigmund, Steven G. Johnson   +5 more
wiley   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

Multiecho Fat‐Water Spiral MR Elastography With Distributed Encoding for Simultaneously Imaging Brain and Skull Displacement

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To introduce a novel multiecho, multishot spiral MR elastography (MRE) sequence to image brain and skull displacement simultaneously using a joint fat‐water image reconstruction and distributed motion encoding. Methods Multiple echo times were implemented into a high‐resolution multishot spiral MRE sequence to capture water‐based brain
Alexa M. Diano, Alex M. Cerjanic, Olivia M. Bailey, Mary K. Kramer, Joy Mojumder, Ruth J. Okamoto, Philip V. Bayly, Dzung L. Pham, Curtis L. Johnson   +8 more
wiley   +1 more source

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler, Kush Mehta, Danica Sanders, Cathy Chin, Hannah Zivalic, Judith Carey, Alexandra McCaffrey, Pravin Pant, Carl Lewenhaupt, Sarah Luppino, Gabriel Jacobs, Shea Golden, Ryan Gifford, Erica Scirocco, Mackenzie Keegan, Munaf Hatem, Taravat Yazdanian, Sanem P. Uysal, Natalie Susco, Shauna Schwartzman, Karen Branch, Kathryn E. Hall, Joanna Barnas, Jenny Lam, Jennifer Hagar, Carol Ann Hannan, Sabrina Paganoni, James D. Berry, Mark Garret, Jennifer Scalia, Suma Babu   +30 more
wiley   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

Naval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

Polymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick, Kristi S Anseth, Tayler S Hebner   +2 more
wiley   +1 more source