Results 141 to 150 of about 237 (207)

A Lipid with Lewis Pair‐Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Lewis pair‐integrated lipids (Lp‐lipids), combining targeted delivery and stimuli‐responsive are developed for antibiotic delivery. These lipids form nanoparticles that bind biofilms via boronate ester bonds and respond to acidic pH, H2O2, and ATP, enabling controlled drug release.
Xiaojian Yan   +11 more
wiley   +1 more source

Dual‐Wavelength Responsive Hydrogel Glue with Visible‐Light Bonding and UV‐Triggered Debonding via Ortho‐Nitrobenzyl Cleavage

open access: yesAdvanced Science, EarlyView.
A dual‐wavelength responsive hydrogel glue achieves orthogonal control of bonding and debonding: visible light drives crosslinking via acrylic acid, while ortho‐nitrobenzyl (ONB) units enable rapid UV‐triggered network cleavage. This smart adhesive offers strong adhesion, fast on‐demand debonding, and spatiotemporal precision for potential applications
Huaming Wang   +9 more
wiley   +1 more source

Unveiling Exciton‐Plasmon Polariton Coupling Regions via Polarization‐Enhanced Optical Nanoscopy

open access: yesAdvanced Science, EarlyView.
Polarization‐enhanced single‐molecule localization microscopy, utilizing a liquid crystal variable retarder (LCVR), actively controls the on‐off intensity modulation of fluorophores. This active intensity modulation improves the localization accuracy of the point spread function (PSF), enabling high‐contrast super‐resolution imaging with significantly ...
Bin Chan Joo   +3 more
wiley   +1 more source

Heme/NADH Mimics Co‐Decorated Allosteric Capsules for Regulating Oxygen Activation and Upregulating Intracellular Methionine Depletion

open access: yesAdvanced Science, EarlyView.
Through modifying the switchable µ‐oxo bridged FeIII‐porphyrins moiety and NADH mimics into a metal‐organic capsule, multiple responsive manners for O2 activation, chemical oxygenation and metabolic transformation have been demonstrated for upregulating intracellular methionine depletion and accumulation of methionine sulfoxide to achieve effective ...
Chunming Ma   +5 more
wiley   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

open access: yesAdvanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen   +15 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

Multifunctional Chiral Halide Perovskites: Advancing Chiro‐Optics, Chiro‐Optoelectronics, and Spintronics

open access: yesAdvanced Science, EarlyView.
This review spotlights key advances in chiral halide perovskite materials and devices, covering device architectures, fabrication methods, and emerging applications like circularly polarized light functions, neuromorphic computing, and spintronics. It explores structure‐property relationships and chirality transfer mechanisms, discusses challenges in ...
Qi Liu, Hui Ren, Qi Wei, Mingjie Li
wiley   +1 more source

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