Results 11 to 20 of about 237 (207)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Detecting rs‐fMRI Networks in Disorders of Consciousness: Improving Clinical Interpretability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Preserved resting‐state functional MRI (rs‐fMRI) networks are typically observed in Disorders of Consciousness (DOC). Despite the widespread use of rs‐fMRI in DOC, a systematic assessment of networks is needed to improve the interpretability of data in clinical practice.
Jean Paul Medina Carrion, Mario Stanziano, Ludovico D'Incerti, Davide Sattin, Stefania Ferraro, Davide Rossi Sebastiano, Francesca Giulia Magnani, Alice Deruti, Davide Fedeli, Ludovico Minati, Francesca Epifani, Marina Grisoli, Matilde Leonardi, Maria Grazia Bruzzone, Anna Nigri, Cristina Rosazza   +15 more
wiley   +1 more source

Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck, Jan Voth, Noëmi Gmahl, Konstantin Jendretzky, Niklas Huntemann, Noah M. Werner, Linea Schmidt, Menekse Oeztuerk, Paula Quint, Christina B. Schroeter, Hans Peter Hartung, Thomas Skripuletz, Gerd Meyer zu Hörste, Tobias Ruck, Sven G. Meuth, Marc Pawlitzki   +15 more
wiley   +1 more source

Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif, Georgios Mangioris, Binxia Yang, Vanessa K. Pazdernik, Jeffrey W. Britton, Divyanshu Dubey, Eoin P. Flanagan, Sarosh R. Irani, Gregory S. Day, Charles L. Howe, A. Sebastian López‐Chiriboga, Andrew McKeon, John R. Mills, Yahel Segal, Michel Toledano, Ivana Vodopivec, Sean J. Pittock, Anastasia Zekeridou   +17 more
wiley   +1 more source

ЗдравÑтвени ризици при изложеноÑÑ‚ на азбеÑÑ‚ во животната Ñредина - преглед на литературата и ÑоÑтојба во Rепублика Mакедонија [PDF]

, 2017
International Agency for Research on Cancer (IARC) in 2009 classified all forms of asbestos as sure human carcinogen (Group 1) for lung cancer, mesothelioma of the pleura, and cancer of the larynx and ovary.
РиÑтовÑка (Ristovska), Гордана (Gordana), Минов (Minov), Јордан (Jordan), КараџинÑка БиÑлимовÑка (Karadzinska Bislimovska), Јованка (Jovanka)   +2 more
core   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

ЭКОНОМИЧЕСКИЕ РЫЧАГИ МУНИЦИПАЛЬНОЙ ПОЛИТИКИ В СФЕРЕ ОХРАНЫ АТМОСФЕРНОГО ВОЗДУХА НА ПРИМЕРЕ ГОРОДА ЛЬВОВА

Mokslo Taikomieji Tyrimai Lietuvos Kolegijose, 2019
Проаналізовано екологічний стан атмосферного повітря у м. Львові. Визначено основні проблеми, що спричиняють надмірне забруднення повітр
Галина Нестеренко
doaj  

ЕВÐЛУÐЦИЈРÐРПРОГРÐМИТЕ ЗРПРЕВЕÐЦИЈРÐÐ ÐœÐЛИГÐИ ÐЕОПЛÐЗМИ ВО РЕПУБЛИКРМÐКЕДОÐИЈР(2005-2015) [PDF]

, 2017
БолеÑти на Ñовремениот живот и водечка причина за морбидитет и морталитет во Република Македонија и во Ñветот Ñе хроничните незаразни болеÑÑ‚
СпаÑовÑки, Моме, ЧингоÑка, Даниела   +1 more
core   +1 more source

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

Arthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond YH Yap, KL Lee, Philip H Li, Iris YK Tang, Chak Sing Lau, Shirley CW Chan   +6 more
wiley   +1 more source

ПОДГОТОВКА СТУДЕНТОВ К ПРОФЕССИОНАЛЬНОЙ ИННОВАЦИОННОЙ ДЕЯТЕЛЬНОСТИ В РАМКАХ СПЕЦИАЛЬНОГО УЧЕБНОГО КУРСА

Mokslo Taikomieji Tyrimai Lietuvos Kolegijose, 2016
Наметившиеся в последнее время тенденции к универсализации образования, прагматичный подход и ориентирование на потребителя, Ð¾Ð¿Ñ€ÐµÐ´ÐµÐ»ÑÑŽÑ ...
Елена Василевская
doaj