Животниот Ñтил и контрола на хроничните незаразни болеÑти [PDF]
, 2018 Non-communicable diseases, also known as modern-life diseases, are the leading cause of morbidity and mortality in the world and in the Republic of Macedonia. The complexity of their occurrence, often associated with multifactorial etiology and lifestyle
СпаÑовÑки (Spasovski), Моме (Mome) +3 more
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
ÐÐТИМИКРОБÐРРЕЗИСТЕÐЦИЈР(ÐМР) ВО ЕВРОПРИ БÐЛКÐÐСКИОТ РЕГИОР– ПРЕГЛЕД ÐРСЕГÐШÐÐТРСОСТОЈБР[PDF]
, 2017 Ðнтимикробната резиÑтенција (ÐМР) претÑтавува глобален проблем, чијшто размер е оÑобено загрижувачки во оние земји каде што не поÑтојат довол
ХриÑтова, КриÑтина +6 more
core +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Плазма-ренинÑка активноÑÑ‚ кај нормотензивните (ÐТ), метакортикоидните (МК), Ñпонатнохипертензивните (СХ) и Ñпонтанохипертензивните "Stroke Prone" (SH-p) [PDF]
, 2017 The level of plasma rennin activity in normotensive (NTR), metacorticoide (MHR), spontaneous hypertensive (SHR) and spontaneous hypertensive stroke prone rats (SHR/SP) has been studied and the results presented in this report.Plasma rennin activity was ...
Петров (Petrov), Стојмир (Stojmir) +1 more
core +1 more source
Screening for Diabetes Type 2 in Primary Health Care [PDF]
, 2015 Вовед. Инцидената на Ð´Ð¸Ñ˜Ð°Ð±ÐµÑ‚ÐµÑ Ñ‚Ð¸Ð¿ 2 е во пораÑÑ‚. Во делот на раното откривање потребно е да Ñе најде интервенција која најдобро ќе ја препоР...
Iliev, Darko +2 more
core +2 more sources
Arthritis Care &Research, Accepted Article.Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti +19 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner +14 more
wiley +1 more source
Инциденција и преваленција на тироиден карцином во Република Маке- донија (1999-2010) [PDF]
, 2017 Epidemiological data indicates that thyroid carcinoma (TC) is the most frequent endocrinological tumors, participating with around 1% from all malignomas.
ТрипуноÑки (Tripunoski), Тони (Toni) +3 more
core +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Arthritis Care &Research, Accepted Article.Background Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined: 1) associations between economic insecurities and PROs; 2) the impact of screening and addressing economic insecurities during ...
Jay Patel +8 more
wiley +1 more source