Животниот Ñтил и контрола на хроничните незаразни болеÑти [PDF]
Non-communicable diseases, also known as modern-life diseases, are the leading cause of morbidity and mortality in the world and in the Republic of Macedonia. The complexity of their occurrence, often associated with multifactorial etiology and lifestyle
СпаÑовÑки (Spasovski), Моме (Mome) +3 more
core +1 more source
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
ÐÐТИМИКРОБÐРРЕЗИСТЕÐЦИЈР(ÐМР) ВО ЕВРОПРИ БÐЛКÐÐСКИОТ РЕГИОР– ПРЕГЛЕД ÐРСЕГÐШÐÐТРСОСТОЈБР[PDF]
Ðнтимикробната резиÑтенција (ÐМР) претÑтавува глобален проблем, чијшто размер е оÑобено загрижувачки во оние земји каде што не поÑтојат довол
ХриÑтова, КриÑтина +6 more
core +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Плазма-ренинÑка активноÑÑ‚ кај нормотензивните (ÐТ), метакортикоидните (МК), Ñпонатнохипертензивните (СХ) и Ñпонтанохипертензивните "Stroke Prone" (SH-p) [PDF]
The level of plasma rennin activity in normotensive (NTR), metacorticoide (MHR), spontaneous hypertensive (SHR) and spontaneous hypertensive stroke prone rats (SHR/SP) has been studied and the results presented in this report.Plasma rennin activity was ...
Петров (Petrov), Стојмир (Stojmir) +1 more
core +1 more source
Screening for Diabetes Type 2 in Primary Health Care [PDF]
Вовед. Инцидената на Ð´Ð¸Ñ˜Ð°Ð±ÐµÑ‚ÐµÑ Ñ‚Ð¸Ð¿ 2 е во пораÑÑ‚. Во делот на раното откривање потребно е да Ñе најде интервенција која најдобро ќе ја препоР...
Iliev, Darko +2 more
core +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Инциденција и преваленција на тироиден карцином во Република Маке- донија (1999-2010) [PDF]
Epidemiological data indicates that thyroid carcinoma (TC) is the most frequent endocrinological tumors, participating with around 1% from all malignomas.
ТрипуноÑки (Tripunoski), Тони (Toni) +3 more
core +1 more source
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns +2 more
wiley +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source

