Results 121 to 130 of about 8,109,854 (251)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Exploring Implicit Emotional Associations With Death in Patients With Current Suicidal Ideation: Results From Novel Attitude Implicit Association Tests for Suicide. [PDF]

Suicide Life Threat Behav
Aschenbrenner LM, Frei A, Knapp D, Forkmann T, Schreiber D, Glaesmer H, Brüdern J, Stein M, Walther S, Gysin-Maillart A.   +9 more
europepmc   +1 more source

Remoção de 17"ð-Etinilestradiol de Águas de Abastecimento, utilizando diferentes Tecnologias de Tratamento Físico-químico

, 2011
Roberto Mauro da Silva Fernandes, Rubens Bresaola   +1 more
openalex   +1 more source

An acoustic phonetic description of the American English /ð/ in two modes [PDF]

, 1991
Josephine Horna
openalex   +1 more source

VARIACIÓN FONÉTICO-FONOLÓGICA DEL MAPUDUNGUN HABLADO POR NIÑOS BILINGÜES DEL ALTO BÍO-BÍO: EL CASO DE LOS FONEMAS FRICATIVOS /ð/ Y /v/ [PDF]

, 2020
Fernanda Narváez-Fuentes, Marisol Henríquez-Barahona   +1 more
openalex   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Probing Intracellular Yeast Metabolism With Deuterium Magnetic Resonance Spectroscopy. [PDF]

NMR Biomed
Anum F, Assaf C, Haj Mohamad F, Anikeeva M, Brahms A, Dey J, Kaltenberger S, Beitz E, Welz L, Annis V, van Gemmeren M, Duckett S, Hövener JB, Pravdivtsev AN.   +13 more
europepmc   +1 more source

Тенденции в Ð¿Ñ€Ð¾Ð¸Ð·Ð²Ð¾Ð´Ð¸Ñ‚ÐµÐ»Ð½Ð¾Ñ Ñ‚Ñ‚Ð° на труда в Ð±ÑŠÐ»Ð³Ð°Ñ€Ñ ÐºÐ°Ñ‚Ð° минна Ð¸Ð½Ð´ÑƒÑ Ñ‚Ñ€Ð¸Ñ [PDF]

, 2020
Ð’Ðμñ Ðμð Ð ̧Ð ⁄ Ðœð ̧Ñ‚Ðμð
openalex  

Stop-like modification of the dental fricative /ð/: An acoustic analysis [PDF]

, 2010
Sherry Y. Zhao
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source