Results 51 to 60 of about 8,109,854 (251)

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Topological analysis of eccentricity-based invariants for second type of dominating David-derived network

open access: yesPhysics Open
The rapid growth of graph theory has sparked interest among analysts, driven by its diverse applications in mathematical chemistry. Closed-form solutions enable rapid property prediction without expensive simulations.
Haidar Ali   +6 more
doaj   +1 more source

To $${d}$$ d , or not to $${d}$$ d : recent developments and comparisons of regularization schemes

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
We give an introduction to several regularization schemes that deal with ultraviolet and infrared singularities appearing in higher-order computations in quantum field theories.
C. Gnendiger   +18 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Some results involving the hypergeometric function Ф2

open access: yesRevista Técnica de la Facultad de Ingeniería, 2011
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Ana lsolina Prieto, Leda Galué
doaj  

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Adiponectin and Leptin—Considerations in Adult Patients with Spinal Muscular Atrophy Type 3

open access: yesDiagnostics
Background: Spinal muscular atrophy (SMA) is a severe neuromuscular disorder characterized by the degeneration of alpha motor neurons in the spinal cord, leading to progressive proximal muscle weakness and paralysis.
Marija Miletić   +7 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

A study of voiceless inter-dental fricative [θ], [ð] sounds and alveolar liquid [r] sound among Chinese learners of English at a higher educational institution in Malaysia

open access: yesJournal of Applied Studies in Language, 2019
This study aims to investigate the pronunciation mistakes in English in accordance with the phonetic study of voiceless and voiced inter- dental fricatives [θ], [ð] and alveolar liquid [r] sounds among Chinese learners of English at University Utara ...
Mizanur Rahman, Dr. Md. Kamrul Hasan
doaj   +1 more source

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