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Mistyping ACE heterozygotes.
PCR methods and applications, 1993 Depar tment of Pathology, Emory University School of Medicine, Atlanta, Georgia 30322 Human angiotensin I-converting enzyme (ACE) insertion/deletion (I/D) polymorphism has been proposed to be a significant predictor of risk for myocardial infarction (MI) V. Shanmugam, K. Sell, B. K. Sahasemanticscholar +1 more sourceTechnical Complications during Veno-Venous Extracorporeal Membrane Oxygenation and Their Relevance Predicting a System-Exchange – Retrospective Analysis of 265 Cases
PLoS ONE, 2014 Objectives Technical complications are a known hazard in veno-venous extracorporeal membrane oxygenation (vvECMO). Identifying these complications and predictive factors indicating a developing system-exchange was the goal of the study.M. Lubnow, A. Philipp, M. Foltan, Tone Bull Enger, D. Lunz, T. Bein, A. Haneya, Ç. Schmid, G. Riegger, T. Müller, K. Lehle +10 moresemanticscholar +1 more sourceCutoff on all Ramanujan graphs [PDF]
, 2015 We show that on every Ramanujan graph $${G}$$G, the simple random walk exhibits cutoff: when $${G}$$G has $${n}$$n vertices and degree $${d}$$d, the total-variation distance of the walk from the uniform distribution at time $${t=\frac{d}{d-2} \log_{d-1 ...E. Lubetzky, Y. Peressemanticscholar +1 more sourceA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts
The Lancet Digital HealthSummary Background Pulmonary complications are the most common cause of death after surgery. This study aimed to derive and externally validate a novel prognostic model that can be used before elective surgery to estimate the risk of postoperative ...L. Bravo, J. Simoes, V. Cardoso, A. Adisa, M. Aguilera, A. Arnaud, B. Biccard, J. Calvache, S. Chernbumroong, M. Elhadi, D. Ghosh, R. Gujjuri, E. Harrison, M. Ho, V. Kasivisvanathan, O. Kouli, H. Lederhuber, Elizabeth Li, M. Löffler, A. Isik, H. Marcus, Janet Martin, Kenneth A. McLean, A. Minaya-Bravo, M. Modolo, D. Nepogodiev, G. Pellino, M. Picciochi, P. Pockney, G. V. van Ramshorst, A. Riad, R. Sayyed, M. Sund, G. Gkoutos, A. Bhangu, J. Glasbey, L. Bravo, V. Cardoso, J. Glasbey, S. Chernbumroong, D. Nepogodiev, J. Simoes, K. Mclean, A. Bhangu, G. Gkoutos, B. Kadir, O. Omar, E. Revell, M. Bahrami-Hessari, Waheed-Ul-Rahman Ahmed, L. Argus, Alasdair Ball, A. Bhangu, E. Bywater, R. Blanco‐Colino, A. Brar, D. Chaudhry, B. E. Dawson, I. Duran, R. Gujjuri, Conor S. Jones, E. Harrison, S. Kamarajah, J. Keatley, S. Lawday, H. Mann, E. Marson, Kenneth A. McLean, Lisa Norman, R. Ots, O. Outani, I. Santos, Catherine Shaw, E. Taylor, I. Trout, Chris Varghese, M. Venn, William Xu, I. Dajti, A. Gjata, S. Kacimi, L. Boccalatte, D. Cox, F. Aigner, Irmgard E. Kronberger, E. Samadov, A. Alderazi, G. Padmore, G. V. van Ramshorst, I. Lawani, A. Cerovac, S. Delibegović, G. Baiocchi, G. Gomes, I. Lima Buarque, M. Gohar, M. Slavchev, C. Nwegbu, A. Agarwal, J. Ng-Kamstra, M. Olivos, Wenhui Lou, D. Ren, J. Calvache, C. J. Perez Rivera, A. Danic Hadzibegovic, T. Kopjar, J. Mihanovic, Pablo Mijahil Avilés Jiménez, N. Gouvas, J. Klát, R. Novysedlák, Nicolas Amisi, P. Christensen, A. El‐Hussuna, S. Batista, Eddy P Lincango-Naranjo, S. Emile, Danilo Alfonso Arévalo Sandoval, H. Dhufera, S. Hailu, M. Mengesha, J. Kauppila, A. Arnaud, Z. Demetrashvili, M. Albertsmeier, M. Löffler, Daniel Kwesi Acquah, B. Ofori, S. Tabiri, S. Metallidis, G. Tsoulfas, M. Aguilera-Arevalo, G. Recinos, Tamás Mersich, Daniel Wettstein, D. Ghosh, G. Kembuan, P. Brouki Milan, Mohammad Hossein Khosravi, M. Mozafari, Ahmed Hilmi, H. Mohan, O. Zmora, G. Gallo, F. Pata, Yuki Fujimoto, N. Kuroda, S. Satoi, M. K. Abou Chaar, F. Ayasra, I. Fakhradiyev, I. Hamdun, Jang Jin-Young, M. Jamal, Lina Karout, A. Gulla, F. Rasoaherinomenjanahary, L. Samison, A. Roslani, Iran Irani Durán Sánchez, D. S. Gonzalez, L. Martinez, María José Martínez, Alejandra Nayen, A. Ramos-De la Medina, J. Nunez, P. Nashidengo, Ashish Shrestha, P. Jonker, S. Kruijff, M. Noltes, P. Steinkamp, Deborah Wright, L. Abdur-Rahman, A. Ademuyiwa, B. Osinaike, J. Seyi-olajide, O. Williams, E. Williams, Sofija Pejkova, Z. Al Balushi, A. Qureshi, Mustafa Abo Mohsen, S. Abukhalaf, M. Cukier, H. Gómez-Fernández, Sebastián Bernardo Shu Yip, Ximena Paola Vasquez Ojeda, M. Sacdalan, P. Major, J. Azevedo, M. Cunha, A. Zarour, E. Bonci, I. Negoi, S. Efetov, V. Kochetkov, A. Litvin, Jc Allen Ingabire, G. Bucyibaruta, Ntirenganya Faustin, S. Habumuremyi, Alphonsine Imanishimwe, Haragirimana Jean de Dieu, E. Munyaneza, Isaie Ncogoza, E. Alameer, A. Ndong, D. Radenkovic, Min-Hoe Chew, F. Koh, James Ngu, A. Panyko, U. Bele, J. Košir, H. Daoud, Ana Minaya Bravo, U. Jayarajah, Dakshitha Wickramasinghe, Mohammed Elmujtba Adam Essa Adam, M. Rutegård, M. Adamina, E. Gialamas, K. Horisberger, M. Alshaar, V. Lohsiriwat, S. Charles, S. Leventoğlu, H. M. Lekuya, H. Lule, Slava Kopetskyi, H. Alsaadi, S. Alshryda, O. Alser, B. Bankhead-Kendall, K. Breen, H. Kaafarani, H. Mashbari, Fernando Bonilla Cal, H. Al-Naggar, M. Maimbo, D. Mazingi, T. Abbott, M. Akhbari, S. Bhanderi, S. Chakrabortee, A. Costas-Chavarri, Andreas K. Demetriades, A. Desai, S. Di Saverio, T. Drake, J. Edwards, J. Evans, M. Fiore, S. Ford, C. Fotopoulou, A. Fowler, K. Futaba, I. Ganly, Harelimana Grace James, E. Griffiths, P. Hutchinson, G. Hyman, Joseph J. Incorvia, R. Jain, M. Jenkinson, T. Khan, Stephen R. Knight, A. Kolias, S. Kudsk-Iversen, Tsun Yu Kwan, E. Leung, Julio Mayol, S. McKay, J. G. Meara, E. Mills, S. Moug, Akshay J. Patel, R. Perinotti, H. E. Rice, Keith J. Roberts, A. Schache, R. Shaw, N. Smart, M. Stephens, G. Stewart, E. Teasdale, R. Vidya, N. Wright, F. Wuraola, E. Agastra, Dariel Thereska, S. Lucchini, Veronica Laudani, C. Chwat, Ivana Ines Pedraza Salazar, D. A. Pantoja Pachajoa, A. Duro, José Alfredo Calderón Arancibia, T. Bright, Paul Hollington, Xuan Zhou, H. Kroon, A. Farfus, John Barker, E. Watson, S. Stevens, H. Latif, A. C. Dawson, Alwin Chuan, Vijayaragavan Muralidharan, E. Wong, Travis Ackermann, M. Pacilli, R. Hodgson, A. Heriot, P. Choong, Wendy Brown, S. Lidder, Justin Yeung, L. Traeger, Guillermo Regalo, R. Gourlay, S. Badiani, C. Koh, S. Putnis, Fayza Haider, Ashrarur Rahman Mitul, N. Komen, B. Dhondt, Serge Cappeliez, M. Pigeolet, M. Schoneveld, J. Stijns, W. Oosterlinck, N. Flamey, Cyrille Kpangon, M. Agbadebo, S. R. Tobome, A. Vieira Barros, S. Aguiar Júnior, H. G. D. A. Campos, Jefferson Gross, Felipe José Fernandez Coimbra, L. P. Kowalski, F. Makdissi, S. Nakagawa, João Pedreira Duprat Neto, J. Vartanian, Guilherme Yazbek, S. Zequi, R. Flumignan, Natalia Jaworska, A. Dell, Harsha Shanthanna, Abdollah Behzadi, C. Nessim, M. Mozel, Pascal St-germain, C. Russell, G. Groot, N. Safieddine, D. Wijeysundera, Antoine Eskander, Sami Chadi, S. Mackenzie, F. Heredia, Julio Villanueva, S. Waissbluth, Roberto Macchiavello, Mario I Escudero, T. Fuentes, X. Mimica, Dinimo Bolivar Saenz, L. Caicedo, Juan Pablo Alzate, Joaquín Luna, Néstor Fabian Pedraza Alonso, Camilo Ortiz Silva, Julia Rodriguez, Liliana Silva-Igua, Martha Torres, L. Trujillo, Albaro José Nieto Calvache, Julián Balanta-Melo, Rafael Figueroa - Casanova, Oscar-Julián García-Montoya, Carlos Andres Marulanda Toro, Maria Clara Mendoza- Arango, Eneida Diaz Martinez, Valentina Gutiérrez Perdomo, Emileth Montenegro, J. Rodriguez-Abreu, G. Abouelnagah, S. Shehata, Ahmed Hossam Eldin Fouad Rida, R. Hassan, M. Saad, Mohamed Reda loaloa, B. Mostafa, M. Qassem, Mohamed Fahmy, H. Abozied, A. Azzam, S. Ghozy, A. Sallam, A. Shehta, M. Abdelkhalek, R. Samaka, Amr Morsy, A. Sherif, M. Abebe, Abraham G. Negussie, T. Fisseha, K. Shumbash, S. Yasin, Y. B. Akililu, A. Megersa, Teshome Tefera, Melatework, B. Atnafu, Bereket Tsegaye, Y. S. Bezabih, Silamlak Sisay, K. Bekele, Moa C Jira, H. Derilo, Eyueal Degefa, Anteneh Tadesse, Melkamu Nidaw, E. Sarjanoja, S. Testelin, S. Boucher, L. Jouffret, Z. Lakkis, A. Zarzavadjian Le Bian, L. Harper, M. Danguy des Déserts, Benoît André, Karem Slim, R. Verhaeghe, A. Police, E. Girard, A. Chebaro, Armande Subayi Nkembi, L. Arnalsteen, Q. Ballouhey, D. Mege, C. Jeandel, E. Duchalais, P. Bouché, G. Manceau, C. Crétolle, E. Hervieux, Noémie Girard, A. Seguin-givelet, S. Gaujoux, B. de Simone, M. Boisson, D. Bergeat, F. Fredon, F. Nappi, R. Kassir, A. Scalabre, F. Migliorelli, A. Ezanno, B. Seeliger, C. Vaysse, Hélène Charbonneau, Vincent Misrai, Olivier Abbo, M. Ángeles, L. Brunaud, A. Modabber, S. Wolf, C. Kamphues, P. Höhn, Tim R. Glowka, Alexander C. Rokohl, U. Bork, G. Fluegen, R. Horch, Andrea Schmedding, Andreas Schnitzbauer, H. Eberbach, Daniela Schlager, F. Spelsberg, L. Keppler, A. Hecker, S. Wolfer, U. Ronellenfitsch, C. Nitschke, C. Peiper, I. Hakami, Stefan Welter, Karine Nikolaieva, A. Roth, J. Lindert, K. Gousias +499 moresemanticscholar +1 more sourceAAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.Stavros Azinas, Marta Carroniwiley +1 more sourceGenetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova +25 morewiley +1 more source
