Results 61 to 70 of about 435 (154)
Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion
Advanced Science, EarlyView.ABSTRACT
Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li +15 morewiley +1 more sourceAtomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2
Advanced Science, EarlyView.Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen Dongyun Kim, Wonjae Ko, Byoung‐Hoon Lee, Sanghoon Kim, Yun Do Kim, Hyunsoo Ahn, Yoon Jung, Chan Woo Lee, Kug‐Seung Lee, Eunhee Gong, Junho Lee, Minho Kim, Taeghwan Hyeon, Su‐Il In +13 morewiley +1 more sourceCarboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease
Advanced Science, EarlyView.The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich +13 morewiley +1 more sourceAn ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism
Advanced Science, EarlyView.The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai +21 morewiley +1 more sourceHepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD
Advanced Science, EarlyView.Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu +28 morewiley +1 more sourceEditorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
, 2016 D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin, H. Abeliovich, A. Arozena, H. Adachi, C. Adams, P. Adams, K. Adeli, P. Adhihetty, S. Adler, G. Agam, R. Agarwal, M. Aghi, M. Agnello, P. Agostinis, Pv Aguilar, J. Ghiso, E. Airoldi, S. A. Ali, T. Akematsu, E. Akporiaye, M. A. Rubeai, G. Albaiceta, C. Albanese, D. Albani, M. Albert, J. Aldudo, H. Algül, M. Alirezaei, I. Alloza, A. Almasan, M. A. Beceril, E. Alnemri, C. Alonso, N. Bonnet, D. Altieri, S. Álvarez, L. A. Erviti, Sandro Alves, G. Amadoro, A. Amano, C. Amantini, S. Ambrosio, I. Amelio, A. Amer, M. Amessou, A. Amon, Zhenyi An, F. Anania, Susan M. K. Andersen, U. Andley, C. Andreadi, N. Abadie, A. Anel, D. Ann, S. Dukie, M. Antonioli, H. Aoki, N. Apostolova, S. Aquila, K. Aquilano, K. Araki, E. Arama, A. Aranda, Jun Araya, A. Arcaro, E. Arias, H. Arimoto, Ar Ariosa, J. Armstrong, T. Arnould, I. Arsov, K. Asanuma, Askanas, E. Asselin, Ryuichiro Atarashi, S. T. Atherton, J. Atkin, Ld Attardi, P. Auberger, G. Auburger, L. Aurelian, R. Autelli, L. Avagliano, M. Avantaggiati, L. Avrahami, S. Awale, N. Azad, T. Bachetti, J. Backer, D. Bae, J. Bae, On Bae, S. Bae, E. Baehrecke, S. Baek, S. Baghdiguian, A. B. Zadworna, Hua Bai, J. Bai, X. Bai, Y. Bailly, Kn Balaji, W. Balduini, A. Ballabio, R. Balzan, R. Banerjee, G. Bánhegyi, Haijun Bao, B. Barbeau, Barrachina, E. Barreiro, B. Bartel, Alberto Bartolomé, D. Bassham, M. Bassi, R. Bast, A. Basu, M. Batista, H. Batoko, M. Battino, K. Bauckman, Bl Baumgarner, K. Bayer, R. Beale, J. Beaulieu, G. Beck, Christoph Becker, J. Beckham, P. Bédard, P. Bednarski, T. Begley, C. Behl, C. Behrends, G. Behrens, K. Behrns, Eloy Bejarano, Amine Belaid, F. Belleudi, G. Bénard, G. Berchem, D. Bergamaschi, M. Bergami, B. Berkhout, L. Berliocchi, Amélie Bernard, Monique Bernard, F. Bernassola, A. Bertolotti, A. Bess, Sébastien Besteiro, S. Bettuzzi, Savita Bhalla, S. Bhattacharyya, S. Bhutia, Caroline A Biagosch, M. Bianchi, M. Piechaczyk, Billes, C. Bincoletto, Baris Bingol, S. Bird, M. Bitoun, I. Bjedov, C. Blackstone, L. Blanc, G. Blanco, H. Blomhoff, E. B. Romero, Stefan Böckler, M. Boes, K. Battaglia, L. Boise, A. Bolino, Andrea Boman, P. Bonaldo, M. Bordi, J. Bosch, Lm Botana, J. Botti, G. Bou, M. Bouché, M. Bouchecareilh, Mj Boucher, M. Boulton, S. Bouret, P. Boya, M. Guittaut, P. Bozhkov, N. Brady, Vm Braga, C. Brancolini, G. Braus, Bravo San Pedro Jm, L. Brennan, E. Bresnick, P. Brest, D. Bridges, M. Bringer, M. Brini, G. Brito, B. Brodin, P. Brookes, E. Brown, Karen P. Brown, H. Broxmeyer, A. Bruhat, P. Brum, Jh Brumell, N. Pierri, B. Rj, S. Buch, A. Buchan, H. Budak, D. Bulavin, S. Bultman, G. Bultynck, Bumbasirevic, Y. Burelle, R. Burke, M. Burmeister, P. Bütikofer, L. Caberlotto, K. Cadwell, M. Cahova, D. Cai, J. Cai, Qian Cai, S. Calatayud, N. Camougrand, M. Campanella, G. Campbell, M. Campbell, S. Campello, R. Candau, I. Caniggia, L. Cantoni, Lizhi Cao, A. Caplan, M. Caraglia, C. Cardinali, SM Cardoso, J. Carew, L. Carleton, Cr Carlin, S. Carloni, Carlsson, D. C. Gutierrez, L. Carneiro, O. Carnevali, Serena Carra, A. Carrier, Bernadette Carroll, Caty Casas, J. Casas, G. Cassinelli, P. Castets, S. C. Obregon, G. Cavallini, I. Ceccherini, F. Cecconi, A. Cederbaum, Ceña, S. Cenci, C. Cerella, D. Cervia, S. Cetrullo, Hassan Chaachouay, H. Chae, A. Chagin, Cy Chai, Gopal Chakrabarti, Georgios Chamilos, Ey Chan, M. Chan, D. Chandra, P. Chandra, CP. Chang, R. Chang, Ty Chang, J. Chatham, S. Chatterjee, S. Chauhan, Y. Che, M. Cheetham, Rajkumar Cheluvappa, Cj Chen, Guang-Chao Chen, Gc Chen, Hongzhuan Chen, Jw Chen, J. Chen, Mingzhou Chen, Peiwen Chen, Quan Chen, Sd Chen, S. Chen, Ss Chen, W. Q. Chen, Wj Chen, Wq Chen, Xiangmei Chen, Y. Chen, Yg Chen, Yue‐Qin Chen, Yj Chen, Yq Chen, Zhong Chen, Alan Cheng, C.-h. Cheng, Hua Cheng, H. Cheong, S. Cherry, J. Chesney, C. Cheung, É. Chevet, H. Chi, Sg Chi, Fulvio Chiacchiera, Hl Chiang, R. Chiarelli, M. Chiariello, M. Chieppa, Ls Chin, M. Chiong, G. Chiu, Dh Cho, S-G Cho, W.Y. Cho, Yy Cho, Ys Cho, A. Choi, E-Ryung Choi, Ek Choi, Jayoung Choi, Meena Choi, Si-On Choi, T. Chou, S. Chouaib, D. Choubey, Choubey, Kc Chow, K. Chowdhury, C. Chu, T. Chuang, T. Chun, Hyewon Chung, Taijoon Chung, Y-J Chung, Y. Chwae, Cianfanelli, R. Ciarcia, Ia Ciechomska, Ciriolo, M. Cirone, S. Claerhout, Mj Clague, J. Clària, P. Clarke, R. Clarke, E. Clementi, C. Cleyrat, M. Cnop, E. Coccia, T. Cocco, P. Codogno, J. Coers, E. Cohen, D. Colecchia, L. Coletto, N. Coll, E. Guyon, S. Comincini, M. Condello, K. Cook, G. Coombs, C. Cooper, J. Cooper, I. Coppens, M. Corasaniti, Marco Corazzari, R. Corbalán, E. C. Termeau, Cordero, C. Ramos, O. Corti, A. Cossarizza, P. Costelli, S. Costes, S. Cotman, A. Montes, S. Cottet, E. Couve, L. Covey, L. Cowart, J. Cox, F. Coxon, C. Coyne, Cragg, R. Craven, T. Crepaldi, J. Crespo, A. Criollo, Crippa, M. Jason de la Cruz, Am Cuervo, J. Cuezva, T. Cui, P. Cutillas, M. Czaja, Czyzyk Krzeska Mf, Rk Dagda, U. Dahmen, Chunsun Dai, W. Dai, Yun Dai, Kn Dalby, L. D. Valle, G. Dalmasso, M. D’Amelio, M. Damme, A. Michaud, C. Dargemont, D. Vm, S. Dasarathy, B. Dasgupta, S. Dash, C. Dass, H. Davey, L. Davids, D. Dávila, R. Davis, T. Dawson, V. Dawson, P. Daza, J. Belleroche, P. Figueiredo, D. Rc, J. Fuente, L. Martino, A. D. Matteis, Deen Gr, A. Milito, M. D. Santi, W. Souza, D. Tata, D. Zio, Jayanta Debnath, Reinhard Dechant, Jp Decuypere, S. Deegan, B. Dehay, B. Bello, Del Re Dp, R. D. Mourroux, L. Delbridge, L. Deldicque, E. D. Axford, Y. Deng, J. Dengjel, M. Denizot, P. Dent, C. Der, Deretic, Benoît Derrien, E. Deutsch, Tp Devarenne, R. Devenish, S. Bartolomeo, N. Daniele, F. Domenico, A. Nardo, S. D. Paola, A. Pietro, L. Renzo, A. Diantonio, G. D. Araya, I. Laviada, Diaz Meco Mt, J. Nido, C. Dickey, R. Dickson, M. Diederich, P. Digard, I. Dikič, D. Sp, C. Ding, W. Ding, Zufeng Ding, L. Dini, J. Distler, A. Diwan, M. Mergny, K. Dmytruk, R. Dobson, Doetsch, K. Dokladny, S. Dokudovskaya +499 moresemanticscholar +1 more sourceIntegrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment
Advanced Science, EarlyView.Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue +17 morewiley +1 more sourceErasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery
Advanced Science, EarlyView.We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent Zachary Rabinowitz, Riley J. Deutsch‐Williams, Ralph Weissleder +2 morewiley +1 more sourceBioinspired Hierarchical Architecture with Water Transport Channels for Strong Adhesion at the Sweating Interface
Advanced Science, EarlyView.To address adhesion failure in sweaty epidermal electronics, this study proposes a cross‐species, multi‐scale biomimetic interface. By modeling staged wet adhesion, it integrates self‐regulating liquid bridges with directional drainage. This design ensures stable, high‐performance flexible sensing in complex physiological environments, offering a ...Jieliang Zhao, Yu Xiang, Heng Wang, Huiqing Xu, Zhong Liu, Lulu Liang, Fengwen Jiang, Xuemei Chen, Wenzhong Wang, Chenqing Liu, Guodong Liu, Shaoze Yan, Xu Hou +12 morewiley +1 more source
