This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti+10 more
wiley +1 more source
Е-кадеринот и неговата улога кај пациентки Ñо Ñерозен оваријален карцином во напреднат Ñтадиум [PDF]
Ovarian cancer is the fifth leading cause of cancer deaths and has the highest mortality rate among gynecologic cancers in women in North America and Europe.The aim of this study wasto analyze the correlation between E-cadherin expression and clinical ...
ÐлулоÑки, Игор
core +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Ðндроид/нозе и нозе/труп индекÑи одредени Ñо абÑорпциметрија Ñо двојно-енергетÑки x-зраци кај Кушинг и не-Кушинг здебелени жени [PDF]
The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
ТодоровÑка (Todorovska), Лидија (Lidija)+1 more
core +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Two classes of ideals determined by integer-valued polynomials [PDF]
If D is a domain with quotient field K, let Int(D) = {f(X) ∈ K[X] | f(d) ∈ D for every d ∈ D} be the ring of integer-valued polynomials over D. It is well known that the binomial polynomials GX n H = X(X−1)...(X−n+1) n!
P.J. CAHEN+3 more
doaj
(K − 1)-Kernels In Strong K-Transitive Digraphs
Let D = (V (D),A(D)) be a digraph and k ≥ 2 be an integer. A subset N of V (D) is k-independent if for every pair of vertices u, v ∈ N, we have d(u, v) ≥ k; it is l-absorbent if for every u ∈ V (D) − N, there exists v ∈ N such that d(u, v) ≤ l.
Wang Ruixia
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Фоликолометријата какао еден параметар за одредување на функцијата на тиреоидната жлезда под нормални и екÑпериментални уÑлови [PDF]
With the use of folicullometry, the foliculles were measured in the experimental and control animals, which were divided in four groups according to the seasons.
ÐšÐ°Ð»Ð°Ð¼Ð°Ñ€Ð°Ñ (Kalamaras), Ðна (Ana)+1 more
core +1 more source
ÐÑÑина, ÑкÑÑÑÐ°Ñ Ð² бÑкваÑ
ÐÐμÐ ⁄ ÑÐ Ñ ÐУÐЬР̄ÐÐÐÐÐ
openalex +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source