Results 171 to 180 of about 6,168,048 (271)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Correction: Effect of intermittent fasting, portfolio-moderate-carbohydrate, and anti-inflammatory diets on cardio-metabolic status in pre-diabetic patients; an open-label randomized clinical trial. [PDF]

Diabetol Metab Syndr
Pasdar Y, Saber A, Rezvani N, Bozorgi S, Moradi S, Cheshmeh S, Niazi H, Najafi F.   +7 more
europepmc   +1 more source

ÐÐÐÐÐ ÐЧÑ-ÐÐТРÐ-Ь-ÐРÐÐÐÐÐУ ÐÐ ÐÐÐÐÐ ÐÐÐÐÐÐÐÐÐÐ ÐРÐÐÐСÐÐÐÐТÐÐ-ÐÐТÐÐÐСÐÐÐÐТÐÐРСÐСТÐÐÐ ÐÐТÐÐ¥ÐÐÐРÐÐ ÐÐЧÐÐÐРЩУРÐÐ ÐРУÐÐРРÐÐÐÐÐÐÐÐÐÐУ

, 2015
Iu V Nikitchenko, Т. В. Бараннік, Iu V Nikitchenko, Sheren Ali, П. А. Каліман   +4 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

ФÑзÑоÑеÑапевÑиÑÐ½Ñ Ð¼ÐµÑоди лÑкÑÐ²Ð°Ð½Ð½Ñ Ñ Ð¿Ð°ÑодонÑологÑÑ

, 2014
С. І. Бойцанюк, М. А. Лучинський, В. В. Сопотніцька   +2 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Taserwest neɣ tafeltira deg umezgun n Ǧamal Benɛuf : Bu Tfuset akked Aneggaru ad yerr tawwurt d imedyaten.

Ussnan
Ǧamal Benɛuf d yiwet seg tgejda n umezgun n teqbaylit, ladɣa s tsuqilin d tserwestin i yexdem i tmiga n yimura igraɣlanen yettwasnen, am tmezgunin n Johann Wolfgang von Gothé akked Tawfiq Lḥakim.
Chabha Ben Matouk
doaj  

Proteomic and genetic predictors and risk scores of cardiovascular diseases in persons living with HIV. [PDF]

Front Cardiovasc Med
Mehta T, Haine L, Baker J, Reilly C, Duprez D, Mistry SS, Steffen BT, Jain MK, Arenas-Pinto A, Polizzotto M, Staub T, Safo SE.   +11 more
europepmc   +1 more source

Ðплив ÑиÑÑÐµÐ¼Ð½Ð¸Ñ ÑмÑÐ½Ð½Ð¸Ñ Ð¿Ð¾ÑÑÑÐµÐ½Ñ Ð½Ð° пеÑебÑг генеÑалÑзованого паÑодонÑиÑÑ Ñ ÑвоÑÐ¸Ñ Ð½Ð° ÑевмаÑоÑдний аÑÑÑиÑ

, 2015
І. П. Мазур, С. І. Сміян, І. І. Білозецький, І. І. Свистун   +3 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source