Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
D-mannose alleviates rotenone-induced PD mouse model through microbiota-gut-brain axis. [PDF]
Hong Y, Ge C, Jin J, Gao Y, Tang Y.
europepmc +1 more source
Bicuspid Aortic Valve: Old and Novel Gene Contribution to Disease Onset and Complications. [PDF]
Sticchi E +16 more
europepmc +1 more source
Fecal Microbiota Transplantation Donor Screening: Is Dientamoeba fragilis a Valid Criterion for Donor Exclusion? A Longitudinal Study of a Swiss Cohort. [PDF]
Moser K +13 more
europepmc +1 more source
Association of genetic variation with age at diagnosis in type 1 diabetes. [PDF]
Vollenbrock CE +17 more
europepmc +1 more source
Association of Vitamin D Status With Mortality and Microbial Spectrum in Late-Onset Neonatal Sepsis: A Comparative Observational Study. [PDF]
Yadav A, Anand P, Gera R, Dawson L.
europepmc +1 more source
One-pot catalytic oxidation for the synthesis of 2-biphenylbenzoxazoles, benzothiazoles and 1-substituted benzimidazoles: a convenient and efficient strategy. [PDF]
Ouyang Y +6 more
europepmc +1 more source

