Results 81 to 90 of about 100 (100)

The Squalene Oil‐in‐Water Nanoemulsion Vaccine Carrier AddaVax Potentiates TLR‐Induced B‐Cell Responses

open access: yesCytometry Part A, EarlyView.
ABSTRACT For vaccination, the mechanisms of action of antigens and of immunostimulatory pathogen‐associated molecular pattern (PAMP) adjuvants are better understood than the roles of the depot, carrier, and other formulation‐related influences. Here, we carried out cytometric studies of vaccine formulations and the effect of adjuvant formulations on B ...
Egest J. Pone   +3 more
wiley   +1 more source

EventFlow: Real‐time neuromorphic event‐driven classification of two‐phase boiling flow regimes

open access: yesDroplet, EarlyView.
We present a real‐time flow regime classification framework that integrates neuromorphic event‐driven sensing with deep recurrent neural networks. Unlike traditional frame‐based approaches, our system captures sparse event streams from an event‐based camera, representing only the dynamic brightness changes at the individual pixel level.
Sanghyeon Chang   +9 more
wiley   +1 more source

Multifunctional Phosphorus Doping: Integrating Enhanced Ionic/Electronic Transport and Interface Optimization for Silicon Oxycarbide Anodes

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Phosphorus doping introduced additional electrons into silicon oxycarbide (SiOC) materials, facilitating fast ion/electron transport. It also induced the formation of more stable and Li‐ion conductive interfaces, contributing to the improvement of electrochemical performance.
Yingying Shen   +9 more
wiley   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing   +4 more
wiley   +1 more source

Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta‐analysis from ILAE Epilepsy Surgery Networks Task Force

open access: yesEpilepsia, EarlyView.
Abstract Intracranial electroencephalographic (iEEG) connectivity analysis is a promising method to localize epileptic networks and guide surgical planning in focal drug‐resistant epilepsy. Despite numerous studies exploring its utility, the added value of iEEG connectivity over standard clinical presurgical evaluation remains unclear.
Nishant Sinha   +15 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Fast ripple‐delta coupling as an early biomarker for post‐traumatic epileptogenesis in repetitive brain injury

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Traumatic brain injury (TBI) can induce posttraumatic epilepsy (PTE), but early biomarkers for epileptogenesis are lacking. We aimed to investigate electrographic biomarkers before and during posttraumatic seizure development. Methods We used a repetitive diffuse TBI model in mice with continuous video‐EEG monitoring up to 4½ months ...
Oleksii Shandra   +7 more
wiley   +1 more source

Automated analysis of postictal generalized electroencephalogram suppression for SUDEP risk stratification

open access: yesEpilepsia Open, EarlyView.
Abstract Sudden unexpected death in epilepsy (SUDEP) affects more than 3000 individuals annually, yet objective and scalable biomarkers to assess risk remain limited. Postictal generalized electroencephalogram suppression (PGES) has been proposed as a potential biomarker, but its quantification is often subjective and variable.
Steve D. Reddy   +3 more
wiley   +1 more source

Probabilistic Multi‐Objective Energy Management System Model for an Energy Hub With PtG Technology for Cost Reduction and System Flexibility Improvement

open access: yesEnergy Science &Engineering, EarlyView.
Overview of the under‐study hub energy model showing the energy conversion and distribution among integrated sources and loads. ABSTRACT In this paper, a probabilistic bi‐objective energy management system (EMS) model is proposed for an energy hub (EH) equipped with renewable energy sources such as photovoltaic and wind turbine connected to the main ...
Mohammad Khoshabi   +3 more
wiley   +1 more source

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

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