Results 131 to 140 of about 399 (151)

A century of art dealing in New York. The rise of American art

open access: yesThe Economic History Review, EarlyView.
Abstract We study art trade in New York between 1870 and 1970, analysing returns on investment by the renowned Knoedler gallery to shed light on the evolution of the American art market. A generalist art gallery should allocate investments to equalize expected returns, with differences in effective returns depending on purchase prices, number of traded
Federico Etro, Elena Stepanova
wiley   +1 more source

What defines response to vagus nerve stimulation in children with drug‐resistant epilepsy? A prospective cohort study from the CONNECTiVOS collaboration

open access: yesEpilepsia, EarlyView.
Abstract Objectives Responsiveness to vagus nerve stimulation (VNS) in children with drug‐resistant epilepsy (DRE) is often defined based on reduction in seizure frequency, typically at the 50% threshold, with limited consideration to the effects of therapy on seizure severity and health‐related quality of life (HRQoL). In the current report, we sought
Farbod Niazi   +38 more
wiley   +1 more source

Honouring the Past, Embracing the Future

open access: yesThe Ecumenical Review, EarlyView.
Abstract The United Church of Canada, founded in 1925, represents an ambitious experiment in church union that blends Methodist, Presbyterian, and Congregationalist traditions. Over the past century, the church has played a pivotal role in shaping Canadian society by advocating for social justice, Indigenous reconciliation, interreligious dialogue ...
Hyuk Cho
wiley   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

open access: yesThe FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés   +19 more
wiley   +1 more source

The CRISPR‐Cas9 knockout DDC SH‐SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross‐sectional structural and functional analysis

open access: yesThe FEBS Journal, EarlyView.
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona   +11 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

open access: yesThe FEBS Journal, EarlyView.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone   +4 more
wiley   +1 more source

Reducing bias in shorebird nest survival rates across a large Arctic landscape

open access: yesIbis, EarlyView.
Reproductive success is a key demographic parameter that can have profound impacts on a species' population trend. Indeed, poor reproductive success has been suggested as a contributing factor to the declines observed in many species of birds, including Arctic‐breeding shorebirds.
Sarah T. Saalfeld   +5 more
wiley   +1 more source

Factors Affecting Root Canal Treatment Case Difficulty, Practitioner Rating of Difficulty and Treatment Complications Among General Dentists and Endodontists: A Prospective Cohort Study From National Dental Practice‐Based Research Network PREDICT Project

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Successful root canal treatment (RCT) is necessary for managing pulpal and periapical disease. The technical quality of RCT affects its outcome. Recognising complicating factors can be important to optimising outcomes. The aims of this study were to compare the practitioner reported case difficulty before and after completion of RCT; and ...
Alan S. Law   +21 more
wiley   +1 more source

Cost‐Effectiveness Analysis of an Intensive Lifestyle Intervention Versus Usual Care for Latino Youth With Prediabetes

open access: yesPediatric Obesity, EarlyView.
ABSTRACT Objective Lifestyle intervention is a cost‐effective approach for preventing type 2 diabetes among adults with prediabetes. The purpose of this study was to examine the cost and incremental cost‐effectiveness ratio (ICER) of an intensive lifestyle intervention compared with usual care among youth with prediabetes.
Armando Peña   +10 more
wiley   +1 more source

The Systematic Normativity of Nicene Theology☆

open access: yesInternational Journal of Systematic Theology, EarlyView.
Abstract The 1700th anniversary of the Nicene Council is an opportune moment to consider the possibility that the production and defense of the Nicene confession represent the fruition and manifestation of a way of doing theology that is perennially valid and normative precisely with respect to its systematic integration of the contents of Christian ...
Khaled Anatolios
wiley   +1 more source

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