Results 61 to 70 of about 399 (151)

Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor, Safiya Al Yazeedi, Janaeya Zuri Baher, Chung Cheung, Don D. Sin, Emmanuel Twumasi Osei   +5 more
wiley   +1 more source

Thymidine Phosphorylase Inhibitory Potential and Molecular Docking Studies of Secondary Metabolites Isolated From Fernandoa adenophylla (Wall. ex G. Don) Steenis

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigates the potential of Fernandoa adenophylla, a South American plant, as a reservoir of compounds with thymidine phosphorylase (TP) inhibitory activity. Through a comprehensive approach combining in vitro assays and molecular docking analysis, we isolated and characterized bioactive compounds from F.
Abdur Rauf, Majid Khan, Umer Rashid, Anees Saeed, Zafar Ali Shah, Zubair Ahmad, Abdulhakeem S. Alamri, Walaa F. Alsanie, Imtiaz Khan, Humaira Hussain, Majid Alhomrani, Marcello Iriti   +11 more
wiley   +1 more source

Study on the effect of co‐plasticization of post‐industrial starch for high‐impact thermoplastic starch development

The Canadian Journal of Chemical Engineering, EarlyView.
High‐impact thermoplastic starch blends through the co‐plasticization methodology. Abstract This study analyzed the effect of employing plasticized or co‐plasticized post‐industrial starch in developing PBAT‐based thermoplastic starch (TPS) blends. In this work, the post‐industrial wheat starch was co‐plasticized with glycerol‐urea, glycerol‐citric ...
Aarsha Surendren, Amar K. Mohanty, Loong‐Tak Lim, Qiang Liu, Bassim Abbassi, Manjusri Misra   +5 more
wiley   +1 more source

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

The Lancet, 2020
M. Voysey, S. A. C. Clemens, S. Madhi, L. Weckx, P. Folegatti, P. Aley, B. Angus, V. Baillie, S. Barnabas, Q. Bhorat, S. Bibi, Carmen Briner, P. Cicconi, A. Collins, Rachel Colin-Jones, C. Cutland, T. Darton, K. Dheda, Christopher J. A. Duncan, Katherine Emary, K. Ewer, L. Fairlie, S. Faust, Shuo Feng, D. Ferreira, A. Finn, A. Goodman, Catherine M. Green, C. Green, P. Heath, Catherine Hill, H. Hill, I. Hirsch, S. Hodgson, A. Izu, Susan A. Jackson, D. Jenkin, Carina C D Joe, S. Kerridge, A. Koen, G. Kwatra, R. Lazarus, A. Lawrie, Alice Lelliott, V. Libri, P. Lillie, R. Mallory, A. V. Mendes, E. P. Milan, A. Minassian, A. McGregor, Hazel Morrison, Y. Mujadidi, A. Nana, P. O'reilly, S. Padayachee, A. Pittella, Emma L Plested, K. Pollock, M. Ramasamy, S. Rhead, A. Schwarzbold, Nisha Singh, Andrew Smith, R. Song, M. Snape, E. Sprinz, R. Sutherland, R. Tarrant, E. Thomson, M. Török, M. Toshner, D. Turner, J. Vekemans, T. Villafana, Marion E. E. Watson, C.J. Williams, Alexander D. Douglas, A. Hill, T. Lambe, S. Gilbert, A. Pollard, Marites Fatola Kushala Jeremy Matthew Kirsty James Yemi A. Aban Abayomi Abeyskera Aboagye Adam Adams Adamson , M. Aban, Fatola Abayomi, K. Abeyskera, J. Aboagye, M. Adam, Kirsty Adams, James Adamson, Yemi Adelaja, Gbadebo Adewetan, Syed Adlou, Khatija Ahmed, Yasmeen Akhalwaya, Saajida Akhalwaya, A. Alcock, Aabidah Ali, E. Allen, Lauren Allen, Thamires C. D. S. C Almeida, Mariana P.S. Alves, Fabio Amorim, Foteini Andritsou, R. Anslow, Matthew Appleby, E. Arbe-Barnes, M. Ariaans, Beatriz Arns, L. Arruda, P. Azi, L. Azi, G. Babbage, Catherine Bailey, K. Baker, M. Baker, Natalie Baker, P. Baker, Lisa Baldwin, Ioana Baleanu, Danieli Bandeira, Anna Bara, Marcella A.S. Barbosa, D. Barker, G. Barlow, Eleanor Barnes, A. Barr, J. Barrett, J. Barrett, L. Bates, Alexander Batten, Kirsten Beadon, Emily R. Beales, Rebecca Beckley, Sandra Belij-Rammerstorfer, Jonathan Bell, D. Bellamy, N. Bellei, Sue Belton, Adam Berg, L. Bermejo, E. Berrie, L. Berry, Daniella Berzenyi, Amy Beveridge, K. Bewley, H. Bexhell, Sutika Bhikha, A. Bhorat, Zaheda E. Bhorat, E. Bijker, G. Birch, S. Birch, Adam Bird, Olivia Bird, K. Bisnauthsing, M. Bittaye, Katherine Blackstone, L. Blackwell, Heather Bletchly, C. Blundell, Susannah R. Blundell, P. Bodalia, B. Boettger, Emma Bolam, E. Boland, Daan Bormans, Nicola Borthwick, Francesca Bowring, Amy Boyd, P. Bradley, T. Brenner, Phillip J. Brown, Claire Brown, Charlie Brown-O’Sullivan, Scott Bruce, Emily Brunt, R. Buchan, W. Budd, Yusuf A. Bulbulia, Melanie Bull, J. Burbage, Hassan Burhan, Aileen Burn, K. Buttigieg, N. Byard, Ingrid Cabera Puig, Gloria Calderon, A. Calvert, Susana Camara, Michelangelo Cao, F. Cappuccini, J. R. Cardoso, M. Carr, Miles W. Carroll, A. Carson-Stevens, Y. D. M. Carvalho, José A.M. Carvalho, Helen R. Casey, Paul Cashen, T. Castro, Lucia Carratala Castro, K. Cathie, A. Cavey, J. Cerbino-Neto, Jim Chadwick, David Chapman, S. Charlton, I. Chelysheva, Oliver Chester, S. Chita, J. Cho, Liliana Cifuentes, Elizabeth Clark, M. Clark, A. Clarke, E. Clutterbuck, S. Collins, Christopher P. Conlon, S. Connarty, N. Coombes, Cushla Cooper, R. Cooper, L. Cornelissen, T. Corrah, Catherine Cosgrove, Tony Cox, Wendy E. M. Crocker, Sarah Crosbie, L. Cullen, Daniel P. Cullen, D. Cunha, C. Cunningham, Fiona C. Cuthbertson, S. F. D. da Guarda, Larissa P. da Silva, B. Damratoski, Z. Dános, Maria Thaynná Cintra Dantas, Paula Darroch, M. Datoo, C. Datta, M. Davids, Sarah L. Davies, Hannah Davies, Elizabeth Davis, Judith Davis, John Davis, Maristela Miyamoto de Nobrega, Lis Moreno De Oliveira Kalid, David Dearlove, T. Demissie, A. Desai, Stefania Di Marco, Claudio Di Maso, M. Dinelli, Tanya Dinesh, Claire Docksey, C. Dold, T. Dong, F. Donnellan, Tannyth Gomes dos Santos, T. G. dos Santos, E. P. Dos Santos, N. Douglas, Charlotte Downing, Jonathan Drake, R. Drake-Brockman, Kimberley Driver, R. Drury, S. Dunachie, Benjamin S. Durham, Lidiana Dutra, N. Easom, Samual van Eck, M. Edwards, N. Edwards, Omar M. El Muhanna, Sean C. Elias, Mike Elmore, M. English, Alisgair Esmail, Yakub Moosa Essack, Eoghan Farmer, Mutjaba Farooq, Madi Farrar, Leonard Farrugia, B. Faulkner, S. Fedosyuk, S. Felle, Shuo Feng, Carla Ferreira da Silva, Samantha M. Field, Richard Fisher, A. Flaxman, James Fletcher, Hazel Fofie, Henry Fok, K. Ford, J. Fowler, P. Fraiman, E. Francis, M. M. Franco, J. Frater, Marilúcia S.M. Freire, Samantha H. Fry, Sabrina Fudge, J. Furze, Michelle Fuskova, Pablo Galian-Rubio, E. Galiza, Harriet Garlant, Madita Gavrila, Ailsa Geddes, Karyna A. Gibbons, Ciarán Gilbride, Hardeep Gill, S. Glynn, K. Godwin, Karishma Gokani, Ursula Carvalho Goldoni, Maria Goncalves, Isabela Gonzalez, J. Goodwin, Amina Goondiwala, Katherine Gordon-Quayle, Giacomo Gorini, Janet Grab, Lara Gracie, M. Greenland, N. Greenwood, Johann Greffrath, M. Groenewald, Leonardo Grossi, Gaurav Gupta, M. Hackett, B. Hallis, M. Hamaluba, Elizabeth Hamilton, Joseph Hamlyn, Daniel Hammersley, Aidan T. Hanrath, Brama Hanumunthadu, S. Harris, Clair Harris, Tara Harris, T. Harrison, D. Harrison, Thomas C. Hart, Birgit Hartnell, Shadin Hassan, J. Haughney, Sophia Hawkins, J. Hay, Ian Head, J. Henry, Macarena Hermosin Herrera, D. Hettle, J. Hill, Gina Hodges, E. Horne, M. Hou, C. Houlihan, Elizabeth Howe, Nicola Howell, Jonathan Humphreys, H. Humphries, K. Hurley, Claire Huson, A. Hyder-Wright, C. Hyams, S. Ikram, Alka Ishwarbhai, M. Ivan, Poppy Iveson, Vidyashankara G. Iyer, Frederic Jackson, Jeanne De Jager, S. Jaumdally, H. Jeffers, Natasha Jesudason, Bryony Jones, Kathryn L. Jones, E. Jones, Chris Jones, Marianna Rocha Jorge, A. Jose, A. Joshi, Eduardo A.M.S. Júnior, Joanne Kadziola, Reshma Kailath, Faeeza Kana, Konstantinos Karampatsas, Mwila Kasanyinga, J. Keen, Elizabeth J Kelly, Dearbhla M. Kelly, Debbie Kelly, S. Kelly, D. Kerr, R. Kfouri, Liaquat A. Khan, B. Khozoee, Sarah Kidd, Annabel Killen, J. Kinch, Patrick Kinch, L. King, Thomas B. King, L. Kingham, P. Klenerman, Francesca Knapper, Julian C. Knight, Daniel Knott, S. Koleva, Matilda Lang, G. Lang, Colin Larkworthy, Jessica P. J. Larwood, R. Law, E. Lazarus, Amanda Leach, E. Lees, Nana-Marie Lemm, Á. Lessa, Stephanie Leung, Yuanyuan Li, A. M. Lias, K. Liatsikos, Aline Linder, Samuel Lipworth, Shuchang Liu, Xinxue Liu, A. Lloyd, Stephanie Lloyd, L. Loew, R. Lopez Ramon, L. Lora, V. Lowthorpe, Kleber Luz, J. C. Macdonald, Gordon Macgregor, Meera Madhavan, David O. Mainwaring, E. Makambwa, Rebecca A. Makinson, M. Malahleha, Ross Malamatsho, Garry Mallett, Kushal Mansatta, Takalani Maoko, K. Mapetla, Natalie Marchevsky, S. Marinou, E. Marlow, Gabriela N. Marques, P. Marriott, Richard P. Marshall, Julia L Marshall, Flávia J. Martins, Masebole Masenya, Mduduzi S. L. Masilela, S. Masters, M. Mathew, Hosea Matlebjane, Kedidimetse Matshidiso, O. Mazur, A. Mazzella, Hugh McCaughan, Joanne Mcewan, J. McGlashan, Lorna McInroy, Zoe McIntyre, D. Mclenaghan, Nicky McRobert, Steve McSwiggan, C. Megson, Savviz Mehdipour, Wilma Meijs, Renata N.Á. Mendonça, A. Mentzer, N. Mirtorabi, C. Mitton, Sibusiso Mnyakeni, Fiona Moghaddas, Kgaogelo Molapo, Mapule Moloi, M. Moore, M. I. Moraes-Pinto, Marni Moran, Ella Morey, R. Morgans, S. Morris, Sheila Morris, H. Morris, Franca Morselli, Gertraud Morshead, R. Morter, Lynelle Mottal, A. Moultrie   +499 more
semanticscholar   +1 more source

Quantifying the Influence of Poly(Ethylene glycol) on the Micelle Formation of Nonionic Detergents

ChemPlusChem, EarlyView.
The influence of poly(ethylene glycols) (PEG) with different molecular weights on the critical micelle concentration of nonionic detergents is quantified based on fluorescence spectra of 8‐anilinonaphthalene‐1‐sulfonate (ANS) and found to depend on the concentration of oxyethylene (OE) units rather than polymer length.
Frank Müh, Julia Gätcke, Athina Zouni
wiley   +1 more source

Constructing a cave sediment stratigraphy for the Dachstein Massif sheds light on landscape evolution (Eastern Alps)

The Depositional Record, EarlyView.
Five large Alpine cave systems on the Dachstein (Austria) were investigated and 35 sediment profiles or outcrops between 860 m a.s.l. and 1945 m a.s.l. were analysed. An altitude‐dependent overall stratigraphy is established and depositional conditions and palaeo‐environments are reconstructed.
Franziska Holzer, Lukas Plan, Susanne Gier   +2 more
wiley   +1 more source

Lung ultrasound and mortality in a cardiogenic shock population: A prospective registry‐based analysis

European Journal of Heart Failure, EarlyView.
Lung ultrasound (LUS) and mortality in cardiogenic shock (CS) patients. Abstract Aims Lung ultrasound (LUS) is a widely used technique to assess de‐aeration in critically ill patients with respiratory failure. There is paucity of data on LUS in cardiogenic shock (CS).
Guido Tavazzi, Costanza Natalia Julia Colombo, Matteo Pagnesi, Maurizio Bertaina, Andrea Montisci, Simone Frea, Marco Marini, Martina Briani, Lisa Patrini, Francesca Rossi, Letizia Bertoldi, Giulia Maj, Giovanna Viola, Carlotta Sorini Dini, Serafina Valente, Gaetano Maria De Ferrari, Nuccia Morici, Federico Pappalardo, Alice Sacco, on behalf of the Altshock Group   +19 more
wiley   +1 more source

Kidney injury in patients with heart failure‐related cardiogenic shock: Results from an international, multicentre cohort study

European Journal of Heart Failure, EarlyView.
Kidney injury in heart failure‐related cardiogenic shock. AKI, acute kidney injury; CI, confidence interval; eCPR, extracorporeal cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; OR, odds ratio; VA‐ECMO, veno‐arterial extracorporeal membrane oxygenation.
Jonas Sundermeyer, Caroline Kellner, Benedikt N. Beer, Lisa Besch, Angela Dettling, Letizia Fausta Bertoldi, Stefan Blankenberg, Jeroen Dauw, Dennis Eckner, Ingo Eitel, Tobias Graf, Patrick Horn, Joanna Jozwiak‐Nozdrzykowska, Paulus Kirchhof, Stefan Kluge, Axel Linke, Ulf Landmesser, Enzo Lüsebrink, Nicolas Majunke, Norman Mangner, Sven Möbius Winkler, Peter Nordbeck, Martin Orban, Federico Pappalardo, Matthias Pauschinger, Michal Pazdernik, Alastair Proudfoot, Matthew Kelham, Tienush Rassaf, Hermann Reichenspurner, Clemens Scherer, P. Christian Schulze, Robert H.G. Schwinger, Carsten Skurk, Marek Sramko, Guido Tavazzi, Holger Thiele, Luca Villanova, Nuccia Morici, Ephraim B. Winzer, Dirk Westermann, Benedikt Schrage   +41 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection

Exploration, EarlyView.
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang, Maike Zheng, Yun Zhang, Yu Xue, Sibo Long, Chaohong Wang, Qing Sun, Jun Yan, Yiheng Shi, Bin Yang, Shang Ma, Tiantian Zhang, Lei Cao, Yan Chen, Wenfu Ju, Jing Zhang, Yan Zhao, Mengqiu Gao, Laurence Don Wai Luu, Xinting Yang, Guirong Wang   +20 more
wiley   +1 more source