Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
БезбедноÑта во Ñообраќајот на патиштата – предизвици за јавноздравÑтвен одговор [PDF]
, 2018 Road traffic safety is a high-priority public health problem. In the world annually, around 1.25 million people die on roads as a result of road traffic accidents (2.1% of global mortality), and 20-50 million people are injured and remain with life-long ...
Тозија (Tozija), Фимка (Fimka)
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Компарација на шеÑÑ‚ минутниот теÑÑ‚ на одење кај деца Ñо различни невромуÑкулни болеÑти и здрави деца на возраÑÑ‚ од 5 до 14 години [PDF]
, 2017 The aim of this study was to determinate the importance of 6MWT in children diagnosed with neuromuscular diseases. We evaluated the distances walked and the level of fatigue manifested.
Sabolik, Vesna +8 more
core +1 more source
Зачем программирование грамотному человеку? (Ñ Ñ Ñ Ðµ)
, 2012 Ivan Travkin
openalex +4 more sources
Ð¡ÑŠÑ‰Ð½Ð¾Ñ Ñ‚ и Ð¿Ñ€Ð°ÐºÑ‚Ð¸Ñ‡ÐµÑ ÐºÐ¸ Ð¸Ð·Ð¼ÐµÑ€ÐµÐ½Ð¸Ñ Ð½Ð° Ð»Ð¸Ð´ÐµÑ€Ñ Ñ‚Ð²Ð¾Ñ‚Ð¾ в Ð¼ÐµÐ¶Ð´ÑƒÐ½Ð°Ñ€Ð¾Ð´Ð½Ð¸Ñ Ð¼ÐµÐ½Ð¸Ð´Ð¶Ð¼ÑŠÐ½Ñ‚ [PDF]
, 2020 СР̧Ð ⁄ ÐμÐ ⁄ Ð ⁄ СР̧Ð ⁄ ÐμÐ ⁄ Ð ⁄ Ð ⁄ Ð
openalex
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
restauration de l'Église Notre-Dame de la Candelaria de Quinterquén, île de Caucachué, Chiloé, Chili [PDF]
, 2019 The following article shows the path of a work team in addressing a process of heritage restoration with a community integration approach, taking up the tradition of minga as method.
Ciudad Bazaul , Cristina +1 more
core +1 more source