Results 41 to 50 of about 5,638,603 (255)
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Животниот Ñтил и контрола на хроничните незаразни болеÑти [PDF]
Non-communicable diseases, also known as modern-life diseases, are the leading cause of morbidity and mortality in the world and in the Republic of Macedonia. The complexity of their occurrence, often associated with multifactorial etiology and lifestyle
СпаÑовÑки (Spasovski), Моме (Mome)+3 more
core +1 more source
The Role of Metabolic Syndrome in the Development and Progression of Chronic Renal Failure [PDF]
Метаболичкиот Ñиндром Ñтанува Ñе поголем здравÑтвен проблем во Ñветот, како во земјите во развој така и во виÑоко развиените земји.
Barjaktarova Prosheva, Tatjana+1 more
core +2 more sources
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
The Role of Nurse in Macedonian Bank for Human DNA [PDF]
ОСÐОВÐ: Банка за хумана ДÐК (хДÐÐМКД) претÑтавува Ñкладирање на примерок на ДÐК од поединецот, како и нејзино безбедно и долгорочно чување Ñо цел
Cvetkovska, Elena, Spiroski, Mirko
core +2 more sources
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Letter: Changes in Blood Lactates during Ergometric Testing on Professional Football Players during One Half Season Competitions (Maced Med Electr J. 2015 Oct 02; 2015;50012. http://dx.doi.org/10.3889/mmej.2015.50012) [PDF]
ПоднеÑени Ñе забелешки од ИнÑтитутот за физиологија при МедицинÑкиот факултет во Скопје за автентичноÑта, плагијаризмот и другите етички Ð¾Ñ ...
Spiroski, Mirko
core +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source