Results 21 to 30 of about 408 (186)

Clostridium difficile Strains Associated with Nosocomial Infections - Laboratory Diagnosis, Prevalence, Susceptibility and Molecular Characterization of the Isolates [PDF]

, 2015
Иако во минатото не и Ñе придаваше големо значење на оваа бактерија, Ð´ÐµÐ½ÐµÑ Clostridium difficile е еден од најзначајните агенÑи кои Ñе поврзуваат Ñо Ð¸Ð½Ñ ...
Mihajlov, Kiril, Trajkovska Dokic, Elena
core   +2 more sources

Pull-Out Test and the Effects оf Using Different Types оf Cements and Upgrading Systems оn Endodontic Treated Teeth [PDF]

, 2015
ОСÐОВÐ: Секоја дентална надградба за да ги задоволи оÑновните протетички принципи, треба да овозможи долготрајна и Ñигурна ретенција Ñо ÐºÐ¾Ñ ...
Jovanovski, Sasho, Jurukovska Shotarovska, Vesna, Kapusevska, Biljana   +2 more
core   +2 more sources

Food Allergy Based on Serum Specific IgE in Republic of Macedonia [PDF]

, 2015
ОСÐОВÐ:  Ðлергијата кон храна Ñе дефинира како неÑакан имун одговор кој Ñе јавува при повторувачки изложувања на било кој вид на храна и може д
Efinska-Mladenovska, Olivija, Hristomanova Mitkovska, Slavica, Petlichkovski, Aleksandar, Spiroski, Mirko, Trajkov, Dejan   +4 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Фоликолометријата какао еден параметар за одредување на функцијата на тиреоидната жлезда под нормални и екÑпериментални уÑлови [PDF]

, 2017
With the use of folicullometry, the foliculles were measured in the experimental and control animals, which were divided in four groups according to the seasons.
ÐšÐ°Ð»Ð°Ð¼Ð°Ñ€Ð°Ñ (Kalamaras), Ðна (Ana), Коцева (Koceva), Владанка (Vladanka) Д. (D.)   +1 more
core   +1 more source

Зголемени вредности на IL-8 во ран втор триместар и нивната поврзаност со предвремено раѓање

, 2020
Цитокините (IL-1, IL-6, IL-8, TNF- Alfa) се од исклучително значење во бременоста и тие се продуцираат од страна на постелката во амнионската течност и
Aleksandar Petlickovski, Iva Malahova- Gjoreska, Ivi Kaev, Katerina Nikoloska   +3 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Tumescent technique as regional anesthesia

, 2020
Тумесцентната техника е техника на инфилтрација во супкутаното ткиво на голем волумен пуфериранфизиолошки раствор во кој е потопена мала
Mare Stevkovska, Violeta Nikodinovska Vasilevska   +1 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source