Results 51 to 60 of about 6,426,023 (249)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Названия налима (Lota Lota) в марийских ­диалектах [Names for Burbot (Lota Lota) in Mari Dialects]; pp. 279-284 [PDF]

open access: yesLinguistica Uralica, 2019
The article is about the analysis of the designations of burbot (Lota Lota) in Mari dialects. Tha analysis has allowed to determine six naming units of which one is of Finno-Ugric origin (шамба), two are of Mari orgin (мокшынчо, шiмгол)
Elena Voronina
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

N-[4-(β-d-Allopyranosyloxy)benzylidene]methylamine

open access: yesActa Crystallographica Section E, 2009
The title compound, C14H19NO6, was synthesized by the condensation reaction between hecilid (4-formylphenl-β-d-allopyranoside) and methylamine in methanol.
Shu-Fan Yin   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Ðндроид/нозе и нозе/труп индекÑи одредени Ñо абÑорпциметрија Ñо двојно-енергетÑки x-зраци кај Кушинг и не-Кушинг здебелени жени

open access: yes, 2018
The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
ШубеÑка-Стратрова (Shubeska Stratrova), Славица (Slavica)   +1 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Морбили во фаза на задолжителна вакцинација

open access: yes, 2016
The conclusion of the authors is that, beside the vaccination, measles are still present in our pathology.The most frequent and the hardest complications are respiratory ones as bronchopneumonia, pneumonia, bronchitis, bronchiolitis, stomatitis, and ...
Караџов (Karadzhov), Зоран (Zoran)   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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