Results 231 to 240 of about 6,154,850 (254)

Effects of Irrigation Practices and N Addition Rates on Wheat Nutrient Accumulation and Utilization in Dryland. [PDF]

Plants (Basel)
Zhao C, Ren K, Sun Y, Xie Q, Zhang S, Yang M, Wu S, Huang M, Wu J, Li Y.   +9 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Association of Serum Vitamin D With Macular Microvascular Structure in Type 2 Diabetic Mellitus Without Diabetic Retinopathy: A Cross-Sectional Study. [PDF]

J Diabetes Res
Yang H, Ma X, Pan Y, Zheng S, Zheng H, Xia Z.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Associations Between Vitamin D Status and Clinical Presentation Among French Inpatients With Substance Use Disorders. [PDF]

Addict Biol
Pavirani L, Seelarbokus BA, Marinelli L, Desnavailles P, Berthoz S, Fatseas M.   +5 more
europepmc   +1 more source

Vitamin D Status in Rheumatology Patients with Inflammatory Compared with Non-Inflammatory Diagnoses: Inflammatory and Autoimmune Markers Are Not Associated with Vitamin D Levels. [PDF]

Nutrients
Schäfer A, Kovacs MS, Nigg A, Feuchtenberger M.   +3 more
europepmc   +1 more source

Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy. [PDF]

Neurology
Xiao F, Zhang Y, Wandschneider B, Binding LP, Giampiccolo D, Fleury M, Delazer L, Pimentel BC, Puntambekar I, Fukuma K, Caciagli L, Sander JW, Duncan JS, Zhou D, Koepp MJ.   +14 more
europepmc   +1 more source