Results 221 to 230 of about 5,986,923 (248)

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Daratumumab plus lenalidomide maintenance in newly diagnosed multiple myeloma after transplant: AURIGA subgroup analyses. [PDF]

Blood Cancer J
Foster L, Anderson LD, Chung A, Chaulagain CP, Pettijohn E, Cowan AJ, Costello C, Larson S, Sborov DW, Shain KH, Silbermann R, Voorhees P, Krevvata M, Pei H, Patel S, Khare V, Cortoos A, Carson R, Lin TS, Badros A.   +19 more
europepmc   +1 more source

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Vitamin D and Muscle Function in a Diverse Hemodialysis Cohort. [PDF]

Can J Kidney Health Dis
Mahdavi S, Rosychuk K, Taskapan H, Tam PY, Sikaneta T.   +4 more
europepmc   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Meta-analyses of clozapine, norclozapine levels and their ratio across three genome wide association studies. [PDF]

Transl Psychiatry
Rask SM, Solismaa A, Ahola-Olli A, Molden E, O'Connell KS, Lyytikäinen LP, Mononen N, Lehtimäki T, Kampman O.   +8 more
europepmc   +1 more source

Novel 2-substituted benzothiazole derivatives: synthesis, <i>in vitro</i> and <i>in silico</i> evaluations as potential anticancer agents. [PDF]

RSC Adv
Azzam RA, Seif MM, El-Demellawy MA, Elgemeie GH.   +3 more
europepmc   +1 more source

Virulence hierarchies within the <i>Mycobacterium tuberculosis</i> complex. [PDF]

Proc Natl Acad Sci U S A
Danchuk SN, Duffy SC, Sullivan J, Beenish Rufai S, McIntosh FA, Lupien A, Harrison LB, Ghasemi Goojani H, Taylor L, Wei Y, Joubert P, Mortensen R, Chen JM, Niroula N, Stevens R, Norleen C, Kapur V, Behr MA.   +17 more
europepmc   +1 more source

Correction. [PDF]

MAbs
europepmc   +1 more source

Smoothened Agonist Treatment Mitigates Vasogenic Edema, Neuroinflammation, and Neurological Dysfunction Following Traumatic Brain Injury in Mice. [PDF]

FASEB J
Michinaga S, Takahashi K, Ogawa Y, Mizuguchi H, Hishinuma S.   +4 more
europepmc   +1 more source