Results 41 to 50 of about 5,986,923 (248)

The genus Diolcogaster Ashmead, 1900 (Hymenoptera, Braconidae, Microgastrinae) from China

ZooKeys, 2011
The genus Diolcogaster Ashmead, 1900 (Hymenopteran, Braconidae, Microgastrinae) from China is revised and keyed, with nine new species, namely D. bifurcifossa sp. n., D. brevivena sp. n., D. grammata sp. n., D. ineminens sp. n., D. laetimedia sp.
Jie Zeng, Jun-Hua He, Xue-xin Chen
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

A restriction estimate for a class of oscillatory integral operators along paraboloid

Journal of Inequalities and Applications, 2019
In this paper we establish a restriction estimate for a class of oscillatory integral operators along a paraboloid, Pd−1:={(x1,…,xd):xd=x12+⋯+xd−12}.
Shaozhen Xu, Wenjuan Li
doaj   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Николай  Ракин,  Реалии в переводах финской прозы на коми язык (на материале произведений Л. Лаулаяйнэн) [Realia in Translations of Finnish Prose into Komi (Based on the Works of Leena Laulajainen)] [PDF]

Linguistica Uralica
The paper deals with the analysis of ways of conveying realia in translations of Finnish prose into Komi. Realia are lexical units to be translated, which denote objects, concepts, or situations that may not exist in the practical experience of speaker ...
Nikolay Rakin
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Revision of the carnivorous snail genus Discartemon Pfeiffer, 1856, with description of twelve new species (Pulmonata, Streptaxidae)

ZooKeys, 2014
Twelve new species of the streptaxid snail genus Discartemon Pfeiffer, 1856 are described from southern Thailand and western Malaysia, D. afthonodontia sp. n., D. circulus sp. n., D. deprima sp. n., D. discadentus sp. n., D. discamaximus sp.
Thanit Siriboon, Chirasak Sutcharit, Fred Naggs, Ben Rowson, Somsak Panha   +4 more
doaj   +1 more source

Protein kinase FAM20C—when subcellular localization matters

FEBS Letters, EarlyView.
FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley   +1 more source