Results 171 to 180 of about 6,245,476 (298)

Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions. [PDF]

Drug Dev Res
Aksel AB, Ozgencil F, Bakar-Ates F, Gunindi HB, Massarotti A, Ozkan E, Kaya SG, Gozelle M, Ozkan Y, Eren G.   +9 more
europepmc   +1 more source

ХХV ÐÑжнаÑÐ¾Ð´Ð½Ð°Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð²Ð°Ñ ÐºÐ°Ð½ÑеÑÑнÑÑÑ âÐелаÑÑÑка-полÑÑкÑÑ Ð¼Ð¾ÑнÑÑ, лÑÑаÑаÑÑÑнÑÑ, гÑÑÑаÑÑÑнÑÑ Ñ ÐºÑлÑÑÑÑнÑÑ ÑÑвÑзÑâ: Ñ Ð³Ð¾Ð½Ð°Ñ Ð¿ÑаÑеÑаÑа ÐлÑжбеÑÑ CмÑлковай

, 2016
Maryna Swistunowa
openalex   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Predictive Value of Systemic Immune-Inflammation Index Combined with D-Dimer Levels and Injury Severity Score for the Prognosis of Patients with Multiple Injuries: A Retrospective Analysis. [PDF]

Open Access Emerg Med
Du X, He Y, Liu X.
europepmc   +1 more source

ÐÑÑледование влиÑÐ½Ð¸Ñ ÑÑÑÑкÑÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑионного поÑÑÑÐµÐ»Ñ Ð½ÐµÐ³Ð¾ÑÑдаÑÑÑвеннÑÑ Ð¿ÐµÐ½ÑионнÑÑ Ñондов по обÑзаÑелÑÐ½Ð¾Ð¼Ñ Ð¿ÐµÐ½ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¼Ñ ÑÑÑÐ°Ñ Ð¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð° Ð´Ð¾Ñ Ð¾Ð´Ð½Ð¾ÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑий

, 2016
Наталья Игоревна Белясова
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Taserwest neɣ tafeltira deg umezgun n Ǧamal Benɛuf : Bu Tfuset akked Aneggaru ad yerr tawwurt d imedyaten.

Ussnan
Ǧamal Benɛuf d yiwet seg tgejda n umezgun n teqbaylit, ladɣa s tsuqilin d tserwestin i yexdem i tmiga n yimura igraɣlanen yettwasnen, am tmezgunin n Johann Wolfgang von Gothé akked Tawfiq Lḥakim.
Chabha Ben Matouk
doaj  

Macrophage anti-bacterial activity is controlled by adenylate kinase 4-mediated mitochondrial DNA synthesis. [PDF]

J Exp Med
Chin WY, Wu CT, Liou GG, Jiang ST, Cheng YS, Lin JS, Wu-Hsieh BA, Miaw SC.   +7 more
europepmc   +1 more source

ÐÐ°Ð´Ð·Ð¾Ñ Ð·Ð° иÑполнением законов оÑганами, оÑÑÑеÑÑвлÑÑÑими дознание и пÑедваÑиÑелÑное ÑледÑÑвие

, 2016
Валерия Валерьевна Малинина
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source