Results 211 to 220 of about 6,245,476 (298)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Intraoperative Degree Misalignment in Toric Intraocular Lens Implantation When Using Conventional Compared to Digital Marking. [PDF]

Clin Ophthalmol
Kandavel R, Dredge J, Jackson H, Landingin J, Henderson SK, Alam T, Hall B.   +6 more
europepmc   +1 more source

ÐоÑлÑÐ´Ð¶ÐµÐ½Ð½Ñ ÐµÑекÑивноÑÑÑ Snort в пÑоÑидÑÑ Ð¼ÐµÑодам ÑканÑÐ²Ð°Ð½Ð½Ñ Ð¿Ð¾ÑÑÑв

, 2017
Chumachenko, Kateryna; Kharkiv National University of Radioelectronics, Ukraine, Chumachenko, Dmytro; National Aerospace University «Kharkiv Aviation Insitute», Ukraine   +1 more
openalex   +1 more source

РазÑабоÑка полиÑики пÑÐ¾Ð´Ð²Ð¸Ð¶ÐµÐ½Ð¸Ñ Ð¾ÑганизаÑии

, 2017
Павел Андреевич Пенкин
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Unraveling the dynamic changes in the intestinal microbiome: impacts on pre-weaning calf health and productivity. [PDF]

J Anim Sci Biotechnol
Song Y, Wen S, Guan LL.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Observation of partonic flow in proton-proton and proton-nucleus collisions. [PDF]

Nat Commun
ALICE Collaboration.
europepmc   +1 more source

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, 2016
Сергій Олександрович; Національний авіаційний університет Гнатюк, Тетяна Олександрівна; Національний авіаційний університет Жмурко, Василь Миколайович; Національний авіаційний університет Кінзерявий   +2 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source