Results 51 to 60 of about 6,426,710 (250)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Морбили во фаза на задолжителна вакцинација

open access: yes, 2016
The conclusion of the authors is that, beside the vaccination, measles are still present in our pathology.The most frequent and the hardest complications are respiratory ones as bronchopneumonia, pneumonia, bronchitis, bronchiolitis, stomatitis, and ...
Караџов (Karadzhov), Зоран (Zoran)   +2 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Anti-N-Methyl-D-Aspartate Receptor Encephalitis

open access: yesPediatric Neurology Briefs, 2013
Investigators at Universities of Barcelona, Pennsylvania, Oviedo, and Valencia, and the Spanish NMDAR Encephalitis Work Group report the clinical features of 20 pediatric patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis seen in a ...
J Gordon Millichap
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Когнитивниот дефицит кај возраÑни пациенти по анеÑтезија во не–кардијалната хирургија

open access: yes, 2017
Studies of the early 21st century indicate that the decline in cognitive functionis as a complication of anesthesia and operative intervention. Whether there would be changes and the amount of changes in mental status will cause a type of anesthesia is a
Трајкова, Радмила   +2 more
core  

Anti-N-Methyl-d-Aspartate Receptor Encephalitis

open access: yesPediatrics and Neonatology, 2011
Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatment-responsive encephalitis associated with anti-NMDA receptor antibodies, which bind to the NR1/NR2 heteromers of the NMDA receptors.
Te-Yu Hung, Ning-Hui Foo, Ming-Chi Lai
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Компарација на шеÑÑ‚ минутниот теÑÑ‚ на одење кај деца Ñо различни невромуÑкулни болеÑти и здрави деца на возраÑÑ‚ од 5 до 14 години

open access: yes, 2017
The aim of this study was to determinate the importance of 6MWT in children diagnosed with neuromuscular diseases. We evaluated the distances walked and the level of fatigue manifested.
Далипи (Dalipi), Ðделина (Adelina)   +8 more
core  

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