Results 51 to 60 of about 725,145 (197)
Background/Objectives: Elevated homocysteine (Hcy) levels are associated with endothelial dysfunction, oxidative stress, and inflammation, contributing to cardiovascular disease development.
Dušan Todorović +10 more
doaj +1 more source
We have performed an analysis of the $$e^+ e^- \rightarrow D^{(*)} {{\bar{D}}}^{(*)}$$ e+e-→D(∗)D¯(∗) data in the region of the $$\psi (4040)$$ ψ(4040) and $$\psi (4160)$$ ψ(4160) resonances which have a substantial overlap and require special care.
M. Bayar, N. Ikeno, E. Oset
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Споредба на лапаро- ÑкопÑка херниоплаÑтика Ñо конвенционална техника кај женÑки деца Ñо индиректна ингвинална хернија [PDF]
The study aims to compare the conventional open technique for treating inguinal hernia versus laparoscopic assisted technique of percutaneous closure of the internal inguinal ring in female children with clinically diagnosed indirect inguinal hernia ...
Симеонов (Simeonov), РиÑто (Risto) +4 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Ðндроид/нозе и нозе/труп индекÑи одредени Ñо абÑорпциметрија Ñо двојно-енергетÑки x-зраци кај Кушинг и не-Кушинг здебелени жени [PDF]
The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
ШубеÑка-Стратрова (Shubeska Stratrova), Славица (Slavica) +1 more
core
The rapid growth of graph theory has sparked interest among analysts, driven by its diverse applications in mathematical chemistry. Closed-form solutions enable rapid property prediction without expensive simulations.
Haidar Ali +6 more
doaj +1 more source

