Results 121 to 130 of about 6,171,578 (254)

Плазма-ренинÑка активноÑÑ‚ кај нормотензивните (ÐТ), метакортикоидните (МК), Ñпонатнохипертензивните (СХ) и Ñпонтанохипертензивните "Stroke Prone" (SH-p) [PDF]

open access: yes, 2017
The level of plasma rennin activity in normotensive (NTR), metacorticoide (MHR), spontaneous hypertensive (SHR) and spontaneous hypertensive stroke prone rats (SHR/SP) has been studied and the results presented in this report.Plasma rennin activity was ...
Петров (Petrov), Стојмир (Stojmir)   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

From the beginning of additional capitalization to July 1, 2017, additional capitalized banks provided the economy with about 13.7 trillion rubles in credits [PDF]

open access: yes, 2017
Original title in Russian is С начала докапитализации по 1 Ð¸ÑŽÐ»Ñ 2017 Ðó. докапитализированные банки предоÑтавили в Ñкономику порÑдка 13,7 трлн руб.
Russian Federation: Accounts Chamber of the Russian Federation
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Quantum-group-invariant D n + 1 2 $$ {D}_{n+1}^{(2)} $$ models: Bethe ansatz and finite-size spectrum

open access: yesJournal of High Energy Physics
We consider the quantum integrable spin chain models associated with the Jimbo R-matrix based on the quantum affine algebra D n + 1 2 $$ {D}_{n+1}^{(2)} $$ , subject to quantum-group-invariant boundary conditions parameterized by two discrete variables p
Holger Frahm   +3 more
doaj   +1 more source

One Method of Solution of an Optimum Investment Portfolio Problem for Risky Assets [PDF]

open access: yes
The problem for choice of an optimum investment portfolio is considered. The square-law form of risk is presented as two-multiple convolution of ковариантного tensor of the covariance matrix and kontravariant vector of weights.
Alexander Milnikov, Mikheil Mamistvalov
core   +1 more source

БезбедноÑта во Ñообраќајот на патиштата – предизвици за јавноздравÑтвен одговор [PDF]

open access: yes, 2018
Road traffic safety is a high-priority public health problem. In the world annually, around 1.25 million people die on roads as a result of road traffic accidents (2.1% of global mortality), and 20-50 million people are injured and remain with life-long ...
Тозија (Tozija), Фимка (Fimka)
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

ЕФЕКТИ ÐÐ CYP3A4 ГЕÐЕТСКИ ПОЛИМОРФИЗÐМ ВРЗ ПОСТОПЕРÐТИВÐÐТРПОТРОШУВÐЧКРÐРФЕÐТÐÐИЛ ПРИ ТРЕТМÐÐ ÐРПОСТОПЕРÐТИВÐÐТРБОЛКР[PDF]

open access: yes, 2017
Минималната ефективна концентрација на опиоиден аналгетик може значајно да Ñе разликува меѓу пациентите.
СпировÑка, Татјана   +8 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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