ð¿ð»ð°ð·ð¼ð¾ññð¾ð½

Results 91 to 100 of about 663 (164)

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour +14 more
wiley +1 more source

, 2017
Александр Андреевич Артемьев
openalex +1 more source

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

Advanced Science, EarlyView.
Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source

, 2016
Татьяна Юрьевна Чернова
openalex +1 more source

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim +10 more
wiley +1 more source

, 2018
Екатерина Семанина
openalex +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen +11 more
wiley +1 more source

, 2017
Андрей Николаевич Тимофеев +1 more
openalex +1 more source

Defect‐Engineered CoSe2 Quantum Dots Exposing Highly Active (111) Facets with Lithiophilic‐Sulfurophilic Functionality for High‐Energy Lithium–Sulfur Batteries

Advanced Science, EarlyView.
Defective CoSe2 QDs confined within carbon microspheres (CoSe2@C) are prepared as an advanced sulfur cathode host material. The exposure of highly active (111) facets and the abundant selenium vacancies not only provides more active sites but also accelerates the catalytic conversion dynamics and lowers the reaction energy barrier of Li–S batteries ...
Xue Li +10 more
wiley +1 more source

, 2016
Светлана Мелконян
openalex +1 more source

computer science
medicine
geology

internal medicine
political science