Results 101 to 110 of about 663 (164)

RNA G‐Quadruplex RIBOTAC‐Mediated Targeted Degradation of lncRNA TERRA

Advanced Science, EarlyView.
This study introduces a selective RNA degradation strategy targeting long noncoding RNA (lncRNA) TERRA, upregulated in ALT (alternative lengthening of telomeres) cancer cells. Using ribonuclease‐targeting chimeras (RIBOTACs), RNase L is recruited to catalytically degrade TERRA, uncovering a novel approach to affect a disease associated lncRNA in ALT ...
Elias Khaskia, Dipak Dahatonde, Raphael I. Benhamou   +2 more
wiley   +1 more source

ÐÑавове Ñа деÑжавне ÑегÑлÑÐ²Ð°Ð½Ð½Ñ ÑÑÑÐ¸Ð·Ð¼Ñ Ñ Ð¡Ð¨Ð

, 2015
Наталія Анатоліївна Опанасюк, Олександр Миколайович Туник   +1 more
openalex   +1 more source

An Efficient CO2‐Upcycling Platform Based on Engineered Halomonas TD with Enhanced Acetate‐Utilizing Capacity via Adaptive Laboratory Evolution

Advanced Science, EarlyView.
An electrochemical system is designed to convert CO2 into CO2‐derived electrolytes (CDE), mainly containing acetate and formate. The underlying mechanism of acetate metabolism in Halomonas TD80 is explored via ALE. Engineered TD80 produced high‐yield diversified products from CDE.
Chi Wang, Ting‐Ting Chen, Yu‐Jiao Yang, Yu‐Xi Li, Yi‐Xin Chang, Yan‐Chun Xiao, Wen‐Tai Guo, Ye Zheng, Rui‐Zhe Deng, Yu‐Xiang Tian, Wei Situ, Hong‐Wei Shen, Yu Chen, Ya‐Bin Wang, Jie Xing, Hui Wang, Lin Xia, Yi‐Na Lin, Jian‐Wen Ye   +18 more
wiley   +1 more source

РозниÑÐ½Ð°Ñ ÑоÑÐ³Ð¾Ð²Ð°Ñ ÑеÑÑ, ее ÑÑÑÑкÑÑÑа и ÑÑнкÑии, оÑновнÑе напÑÐ°Ð²Ð»ÐµÐ½Ð¸Ñ ÑазвиÑиÑ

, 2016
Ксения Юрьевна Федотова
openalex   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

ТоваÑÐ¾Ð²ÐµÐ´Ð½Ð°Ñ Ñ Ð°ÑакÑеÑиÑÑика и оÑенка каÑеÑÑва изделий из ÑÑекла

, 2017
Юлия Валерьевна Кузьмина
openalex   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

ÐÑганизаÑÐ¸Ñ ÐбÑединеннÑÑ ÐаÑий в ÑовÑеменной ÑиÑÑеме междÑнаÑодного пÑава

, 2016
Кристина Анатольевна Овчинникова
openalex   +1 more source

Strong, Recyclable, Bio‐Based Vitrimers by Tailored Rigid‐Flexible Structures for Advanced Carbon Fiber‐Reinforced Polymers

Advanced Science, EarlyView.
A sustainable high‐performance epoxy vitrimer (F9T1) was developed via a rigid‐flexible integrated design using rigid and flexible bio‐based epoxy monomers. F9T1 features superior mechanical property, char‐forming ability, fire safety, chemical degradability and recyclability due to its rigid‐flexible network with abundant dynamic disulfide and ester ...
Yong Guo, Nannan Song, Siqi Huo, Cheng Wang, Guofeng Ye, Min Hong, Ye‐Tang Pan, Tingting Chen, Zhongwei Chen, Yuan Yu, Pingan Song, Hao Wang   +11 more
wiley   +1 more source

ÐÑджеÑиÑование как ÑоÑÑÐ°Ð²Ð½Ð°Ñ ÑаÑÑÑ ÑинанÑового планиÑÐ¾Ð²Ð°Ð½Ð¸Ñ Ð¾ÑганизаÑии

, 2016
Татьяна Валерьевна Тарасова
openalex   +1 more source