Results 121 to 130 of about 663 (164)

From Spark to Flame: ROS‐ and Light‐Cascade Activatable NIR‐II AIE Probe for Precise Tumor Imaging and Self‐Amplifying Phototherapy

open access: yesAdvanced Science, EarlyView.
ROS‐ and NIR light‐cascade activatable NIR‐II AIE theranostic probe (TT‐DHIn) is developed by integration of dihydroindole skeleton with oxidative dehydrogenation reaction mechanism and AIE skeleton with a twisted configuration. Upon ROS in the tumor microenvironment and NIR light activation, TT‐DHIn can achieve dual‐model imaging‐guided precise tumor ...
Xiaohui Chen   +12 more
wiley   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

open access: yesAdvanced Science, EarlyView.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li   +7 more
wiley   +1 more source

Electrically and Geometrically Tunable Photon Pair Entanglement from Ferroelectric Nematic Liquid Crystal

open access: yesAdvanced Science, EarlyView.
By exploiting the strong nonlinear optical response and controllable molecular ordering of ferroelectric nematic liquid crystals (FNLCs), these materials can serve as tunable sources of polarization‐entangled photons. Adjusting the sample geometry or applying an external electric field enables continuous control of the entanglement degree, advancing ...
Sara Klopčič   +3 more
wiley   +1 more source

Wave‐Partition‐Governed Dual‐Site Spallation in Single Crystals

open access: yesAdvanced Science, EarlyView.
Crystalline anisotropy shapes shock‐wave propagation and the resulting damage evolution in single crystals. Large‐scale molecular dynamics and damage modeling uncover a dual‐spallation mechanism driven by anisotropic elasticplastic wave separation, which mitigates damage accumulation.
Youlin Zhu   +6 more
wiley   +1 more source

NIR Ratiometric Fluorescent Antibody‐Drug Conjugate for Metastatic Ovarian Cancer Theranostics and Treatment Response Monitoring

open access: yesAdvanced Science, EarlyView.
In vivo optical imaging enhances antibody‐drug conjugate (ADC) optimization by enabling real‐time monitoring of stimulus‐responsive drug behavior. We report n501‐CYMMAF, a ratiometric theranostic with strong target affinity and low‐dose efficacy for ovarian metastasis.
Cheng Li   +8 more
wiley   +1 more source

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