Results 131 to 140 of about 663 (164)

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

Mussel‐Bioinspired Edible Ca2+‐Crosslinked Alginate Hydrogel Electrodes for Glucose Gastrointestinal Monitoring

open access: yesAdvanced Science, EarlyView.
A fully edible soft electrode is engineered from Ca2⁺‐crosslinked alginate integrated with polydopamine, silver nanoparticles, and food‐grade glucose oxidase. The hybrid hydrogel combines ionic and electronic conduction, enabling efficient glucose‐to‐H2O2 conversion and catalytic reduction in simulated intestinal fluid.
Verdiana Marchianò   +10 more
wiley   +1 more source

Atomic‐Level Structural Characteristics of β‐Relaxation in Metallic Glasses

open access: yesAdvanced Science, EarlyView.
Using in situ synchrotron radiation X‐ray techniques, this study experimentally characterizes β‐relaxation at the atomic scale, linking it explicitly to tricapped trigonal prism (TTP)‐like atomic structures and fast atomic motions. Cyclic heating reveals β‐relaxation as irreversible yet reactivatable through rejuvenation, offering unprecedented insight
Tianding Xu   +7 more
wiley   +1 more source

High‐Security X‐Ray Imaging Encryption Based on Irreversible Acid‐Responsive Radioluminescence Memory Scintillator

open access: yesAdvanced Science, EarlyView.
An irreversible acid‐responsive radioluminescence memory scintillator, Zn1.3Ga1.4Ge0.3O4:Cr3+@Zn2GeO4:Eu3+ (ZGGO@ZGO), is developed in this work. The engineered dual‐layer security system composed of ZGGO@ZGO and ZGO achieves a combined effect of visual misdirection and sequential logic gates requiring acid treatment and CCD detection, significantly ...
Lin Liu   +7 more
wiley   +1 more source

Nucleoside‐Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis

open access: yesAdvanced Science, EarlyView.
A synergistic antibiofilm hydrogel platform (ZBAg@FNP) is developed by encapsulating an organic small‐molecule photothermal agent (FNP) within a silver ion‐mediated supramolecular hydrogel (ZBAg), enabling photothermal disruption of biofilm integrity and controlled Ag⁺ ion release upon irradiation.
Yinghui Wen   +8 more
wiley   +1 more source

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