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Fast ripple‐delta coupling as an early biomarker for post‐traumatic epileptogenesis in repetitive brain injury

Epilepsia Open, EarlyView.
Abstract Objective Traumatic brain injury (TBI) can induce posttraumatic epilepsy (PTE), but early biomarkers for epileptogenesis are lacking. We aimed to investigate electrographic biomarkers before and during posttraumatic seizure development. Methods We used a repetitive diffuse TBI model in mice with continuous video‐EEG monitoring up to 4½ months ...
Oleksii Shandra, Dzenis Mahmutovic, Biswajit Maharathi, Md Adil Arman, Michael J. Benko, Owen Leitzel, Pritom Kumar Saha, Stefanie Robel   +7 more
wiley   +1 more source