Данъчни Ñ Ñ‚Ð¸Ð¼ÑƒÐ»Ð¸ за Ð½Ð°ÑƒÑ‡Ð½Ð¾Ð¸Ð·Ñ Ð»ÐµÐ´Ð¾Ð²Ð°Ñ‚ÐµÐ»Ñ ÐºÐ°Ñ‚Ð° и развойна Ð´ÐµÐ¹Ð½Ð¾Ñ Ñ‚ в Ñ Ñ‚Ñ€Ð°Ð½Ð¸Ñ‚Ðµ от ОИСРи ЕС [PDF]
ЛР̧Ð Ð ̧Ñ Ð”Ð°Ð ⁄ Ñ Ð ⁄ Ð ⁄ Ра
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Prevalence of viral hepatitis in sub-Saharan Africa among the general population: an umbrella review of systematic reviews and meta-analyses. [PDF]
Sticher JS+5 more
europepmc +1 more source
ÐŸÑ€ÐµÐ´Ð¸Ð·Ð²Ð¸ÐºÐ°Ñ‚ÐµÐ»Ñ Ñ‚Ð²Ð° при проектиране, изграждане и ÐµÐºÑ Ð¿Ð»Ð¾Ð°Ñ‚Ð°Ñ†Ð¸Ñ Ð½Ð° Ð¿Ð°Ñ Ð¸Ð²Ð½Ð° Ñ Ð³Ñ€Ð°Ð´Ð° в Ð‘ÑŠÐ»Ð³Ð°Ñ€Ð¸Ñ [PDF]
Ð ̄Ð Ð ⁄ Ñ€ СтР⁄ Ñ Ð ⁄ Ð ⁄ Ð
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Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Association between subclinical hypothyroidism and vitamin D deficiency: Insights from a case-control study. [PDF]
Fatemeh A+4 more
europepmc +1 more source
Приложение на дигиталните технологии в обучението [PDF]
Ð Ð ⁄ ð ̧РДÐμð ⁄ чÐμð
openalex
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source