Results 261 to 270 of about 5,876,256 (302)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Chronic urticaria and vitamin D supplementations: a systematic review. [PDF]

Eur J Med Res
Siddiqui A, Bai A, Kumar H, Mandhwani YR, Bai A, Bai P, Kumar N, Muskan FNU, Jatoi S, Ali Z, Parveen A.   +10 more
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Vitamin D in male sexual functions: unwrapping the sunshine hormone activities in erectile function and beyond. [PDF]

Front Reprod Health
Odetayo AF, Bassey GE, Fajemidagba GA, Okesina KB, Hamed MA.   +4 more
europepmc   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Clinical Outcomes of a Multicenter Study Following Implantation of an Isofocal Optic IOL with Double C-Loop Haptics. [PDF]

Clin Ophthalmol
Daya S, Akahoshi T, Bosc C, Mouchel R, Chassain C, Van Acker E, Di Maria A, Fogagnolo P.   +7 more
europepmc   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Femtosecond-Laser-Assisted Liquid-Interface vs Vacuum-Trephine Keratoplasty: A Comparison of 2 Different Techniques - Retrospective Data Analysis. [PDF]

Clin Ophthalmol
Klimek M, Steiner I, Donner R, Skorpik C, Aschauer J, Schmidinger G, Lammer J.   +6 more
europepmc   +1 more source

Introduction of new quinolone-2-thio-acetamide-propane hydrazide-benzimidazole derivatives as new α-glucosidase and α-amylase inhibitors. [PDF]

Sci Rep
Nikfar P, Karimian S, Safapoor S, Noori M, Dastyafteh N, Ghafouri SN, Mohammadi-Khanaposhtani M, Larijani B, Taslimi P, Mahdavi M.   +9 more
europepmc   +1 more source