Results 101 to 110 of about 6,167,741 (304)

Биомаркери на воÑпаление кај деца Ñо туберкулоза [PDF]

open access: yes, 2017
The aim of this  study was to evaluate  the efficacy of using  appropriate biomarkers of inflammation for diagnosis of tuberculosis in children, monitoring the disease and the effects of the applied  therapy.Material and methods: In this  study, 60 ...
МирчевÑка (Mirchevska), Виолета (Violeta)
core   +1 more source

The Role of Metabolic Syndrome in the Development and Progression of Chronic Renal Failure [PDF]

open access: yes, 2015
Метаболичкиот Ñиндром Ñтанува Ñе поголем здравÑтвен проблем во Ñветот, како во земјите во развој така и во виÑоко развиените земји.
Barjaktarova Prosheva, Tatjana   +1 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Techniques and Methods for Detection and Diagnosis of Oral Premalignant and Malignant Lesions [PDF]

open access: yes, 2015
ОСÐОВÐ: Оралните премалигни и малигни лезии бележат тенденција на доцна детекција, која е на штета на пациентите поради виÑоките Ñтапки нР...
Minovska, Ana   +4 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Boundedness of strong maximal functions with respect to non-doubling measures

open access: yesJournal of Inequalities and Applications, 2016
The main purpose of this paper is to establish a boundedness result for strong maximal functions with respect to certain non-doubling measures in R n $\mathbb{R}^{n}$ . More precisely, let d μ ( x 1 , … , x n ) = d μ 1 ( x 1 ) ⋯ d μ n ( x n ) $d\mu(x_{1},
Wei Ding, LiXin Jiang, YuePing Zhu
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

ИСХРÐÐÐТРИ ЈÐÐ’ÐОТО ЗДРÐВЈЕ – СОСТОЈБÐ, ПОЛИТИКИ И ПРЕДИЗВИЦИ [PDF]

open access: yes, 2017
Студијата  Ð·Ð° глобалното оптоварување Ñо болеÑтите од 2013 година покажа дека факторите на ризик поврзани Ñо иÑхраната Ñе доминантни во Ð½Ð°Ñ ...
СпироÑки, Игор
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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