Results 121 to 130 of about 5,873,779 (302)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

МЕЖБЮДЖЕТ�ЫЕ ОТ�ОШЕ�ИЯ И ОС�ОВ�ЫЕ ��ПР�ВЛЕ�ИЯ ИХ СОВЕРШЕ�СТВОВ��ИЯ (�� ПРИМЕРЕ ГРУЗИИ) [PDF]

open access: yes, 2017
The paper considers inter-budgetary relations as one of the most complex and ambiguous spheres of functioning of state institutions of Georgia. The aim is to identify the problematic aspects of Georgia's budget policy and formulate the key directions for
Abuselidze, George
core   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Razeyev D. N. I. Kant's teleology [PDF]

open access: yesКантовский сборник, 2011
Balanovsky, V. V.
doaj   +1 more source

Since the beginning of the capitalization program, banks have paid fines in the amount of 812.7 million rubles [PDF]

open access: yes, 2018
Original title in Russian is С начала проÐóраммы докапитализации банками уплачено штрафов на Ñумму 812,7 млн рубР...
Russian Federation: Accounts Chamber of the Russian Federation
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Two classes of ideals determined by integer-valued polynomials [PDF]

open access: yesRendiconti di Matematica e delle Sue Applicazioni, 1996
If D is a domain with quotient field K, let Int(D) = {f(X) ∈ K[X] | f(d) ∈ D for every d ∈ D} be the ring of integer-valued polynomials over D. It is well known that the binomial polynomials GX n H = X(X−1)...(X−n+1) n!
P.J. CAHEN   +3 more
doaj  

The system of additional capitalization of banks has not yet begun to work in full force [PDF]

open access: yes, 2015
Original title in Russian is СиÑтема докапитализации банков пока не начала работать в полную ÑиР...
Vilenovich, Perchyan Andrey
core   +1 more source

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