Results 141 to 150 of about 6,167,741 (304)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

СÑавниÑелÑнÑй анализ ÑпекÑÑов ÑоÑолÑминеÑÑенÑии ÑÑда оÑганиÑеÑÐºÐ¸Ñ Ñоединений

, 2017
Григорий Андреевич Верхоглядов
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

ÐÑоÑеÑÑионалÑÐ½Ð°Ñ Ð¸ ÑизиÑеÑÐºÐ°Ñ Ð¿Ð¾Ð´Ð³Ð¾Ñовка военноÑлÑжаÑÐ¸Ñ Ð¡Ð¨Ð

, 2017
Валерий Александрович Щеголев, Валерий Петрович Сущенко   +1 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

D. Seifried, N. Stark: Energiedienstleistungen

Technikfolgenabschätzung – Theorie und Praxis, 1994
TATuP editorial office
doaj   +1 more source

ÐÑÑледование возможноÑÑи ÑÑÐ¸Ð»ÐµÐ½Ð¸Ñ ÑоÑоÑока в геÑеÑоÑÑÑÑкÑÑÑÐ°Ñ II - Ñипа на оÑнове ÑзкозоннÑÑ Ð¿Ð¾Ð»ÑпÑоводников Ð3Ð5

, 2017
Андрей Юрьевич Глотов
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

ÐÑенка ÑÑÑекÑивноÑÑи внедÑÐµÐ½Ð¸Ñ ÐÐШ на плаÑÑоÑме SAP-HR на пÑимеÑе гÑÑÐ¿Ð¿Ñ ÐºÐ¾Ð¼Ð¿Ð°Ð½Ð¸Ð¹ «ÐÐ-Рл

, 2016
Анастасия Олеговна Зубова
openalex   +1 more source

One Method of Solution of an Optimum Investment Portfolio Problem for Risky Assets [PDF]

The problem for choice of an optimum investment portfolio is considered. The square-law form of risk is presented as two-multiple convolution of ковариантного tensor of the covariance matrix and kontravariant vector of weights.
Alexander Milnikov, Mikheil Mamistvalov
core   +1 more source