Results 151 to 160 of about 6,425,400 (257)

Prevalence, Disease Onset and Clinical Outcome in Arginase 1 Deficiency: Cross-Border Surveillance in Germany, Austria, and Switzerland. [PDF]

J Inherit Metab Dis
Scharre S, Hess AL, Gleich F, Garbade SF, Feyh P, Karall D, Baghdasaryan A, Huemer M, Hennermann JB, Hahn A, Lindner M, Gramer G, Luecke T, Kleinelanghorst N, Haeberle J, Lotz-Havla AS, Hoffmann GF, Okun JG, Muetze U, Kölker S.   +19 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

ЕФЕКТИ ÐÐ CYP3A4 ГЕÐЕТСКИ ПОЛИМОРФИЗÐÐœ ВРЗ ПОСТОПЕРÐТИВÐÐТРПОТРОШУВÐЧКРÐРФЕÐТÐÐИЛ ПРИ ТРЕТМÐÐ ÐРПОСТОПЕРÐТИВÐÐТРБОЛКÐ

, 2017
Минималната ефективна концентрација на опиоиден аналгетик може значајно да Ñе разликува меѓу пациентите.
СпировÑка, Татјана, Карталов, Ðндријан, Ðојков, Јордан, ТрајковÑки, Ѓорѓи, МатевÑка-ГешковÑка, Ðадица, ÐамбазовÑка-ТрајковÑка, Вања, ДимовÑки, ÐлекÑандар, Сељмани, Реџеп, КузмановÑка, Биљана   +8 more
core  

Activation of Intestinal Type 3 Innate Lymphoid Cells and Regulatory T Cells Through Free Fatty Acid Receptor 2 Ameliorates Type 1 Diabetes in Mice. [PDF]

Diabetes
Koprivica I, Jonić N, Dimitrijević M, Jevtić B, Mićanović D, Stegnjaić G, Lazarević M, Stanisavljević S, Pilipović I, Radulović N, Saksida T, Mišić D, Zdravković V, Fraser G, Miljković Đ, Stojanović I.   +15 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Современи трендови за развој на информативни ÑиÑтеми

, 2016
ИзваР...
Грнаров, ÐкÑенти
core  

D. Seifried, N. Stark: Energiedienstleistungen - Rezension

Technikfolgenabschätzung – Theorie und Praxis, 1994
Torsten Fleischer
doaj   +1 more source

Multi-omics analysis reveals Parabacteroides distasonis and Kineothrix alysoides as potential key bacterial species associated with anemia in sows. [PDF]

J Anim Sci Biotechnol
Sun L, Chen N, Yang Y, Chen R, Cheng Y, Chen Y, Yan X.   +6 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Ја загубивме битката за работната површина, тврди IBM

, 2016
изваР...
информатика, МЕДИС -
core